Short CV/Education and training

Education and qualifications

  • 1984
    Ecole Normale Superieure in Paris

  • 1990
    PhD in Life Sciences, University of Paris VI

  • 1998
    HDR Biology Research, University Paris XI

Training and professional experience

  • 1991 – 1994
    Post-doc at the Swiss Institute for Research against Cancer (L. Kuhn, Lausanne) and the European Molecular Biology Laboratory (I. Mattaj, Heidelberg, Germany)

  • 1994
    Recruitment as a permanent staff scientist at the CNRS. Laureat of ATIPE "Cell Biology" Young investigator Program

  • 1995 – 2000
    Junior group leader at the Institut Curie

  • Since 2000
    Group leader at the Institut Jacques Monod

  • 2007 – 2008
    Auditor of IHEST

Responsibility currently held

  •  
    Director of Research CNRS

  •  
    Co-director of the Lab of Excellence "WhoAmI?" coordinating 27 research teams

  •  
    Group leader

Selected publications

  • Dargemont, C., Dunon, D., Deugnier, M.A., Denoyelle, M., Girault, J.M., Lederer, F., Le, K.H.D., Godeau, F., Thiery, J.P. and Imhof, B.A. (1989). Thymotaxin, a chemotactic protein, is identical to ? 2-microglobulin. Science 246, 802-806.

  • Dargemont, C. and Kuhn, L.C. (1992). Export of mRNA from microinjected nuclei of Xenopus laevis oocytes. J. Cell Biol. 118, 1-9.

  • Schmidt-Zachmann, M.S.*, Dargemont, C.*, Kuhn, L.C. and Nigg, E.A. (1993). Nuclear export of proteins: The role of nuclear retention. Cell 74, 494-504. (*Co-first authors)

  • Ossareh-Nazari, B., Bachelerie, F. and Dargemont, C.(1997) Evidence for a role of CRM1 in signal-mediated nuclear protein export. Science. 278, 141-144.

  • Cohen, M, Stutz, F., Belgareh, N., Haguenauer-Tsapis, R. and Dargemont, C. (2003) Ubp3p requires a co-factor, Bre5p, to specifically de-ubiquitinate the COPII protein, Sec23p. Nature Cell Biology.5 (7) : 661-667. (cited by F1000)

  • Gwizdek, C*., Iglesias*, N., Rodriguez, M.S., Ossareh-Nazari, B, Hobeika, M., Divita, G., Stutz, F. and Dargemont C. (2006) Ubiquitin-Associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription. PNAS 103(44):16376-81

  • Vitaliano, A., Menant, A., Hobeika, M., Géli, V., Gwizdek, C. and Dargemont, C. (2008) Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethy-lation. Nature Cell Biology 10(11):1365-1371.

  • Iglesias, N., Tutucci, E., Gwizdek, C., Vinciguerra, P., Von Dach E., Corbett, A., Dargemont, C. and Stutz, F. (2010) Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export. Genes and Dev. Sep 1;24(17):1927-38.

  • Dokudovskaya S, Waharte F, Schlessinger A, Pieper U, Devos DP, Cristea IM, Williams R, Salamero J, Chait BT, Sali A, Field MC, Rout MP, Dargemont C. (2011) A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in yeast. Mol. Cell Proteomics. 10(6):M110.006478.

  • Vitaliano-Prunier, A*., Babour A.*, Hérissant, L.*, Apponi, L., Margaritis, T., Holstege, FCP, Corbett, AH, Gwizdek, C.* and Dargemont, C.* (2012) H2B ubiquitylation controls the formation of export-competent mRNP. Mol Cell. 1:132-139.

  • Hayakawa, A., Babour, A., Sengmanivong, L. and Dargemont, C. (2012) Ubiquitylation of the nuclear pore complex controls nuclear migration during mitosis in S. cerevisiae. J. Cell Biol. 1:19-27.

  • Margaritis, T., Oreal, V., Brabers, N., Maestroni, L., Vitaliano-Prunier, A., van Hooff, S., van Leenen, D., Dargemont, C*., Géli V*., Holstege, F*. Dimethymethyletion of H3K4 by Set1 represses transcription of a subset of coding genes by promoting 3?-end antisense RNA production. PLoS Genetics. 8(9): e1002952. doi:10.1371/journal.pgen.1002952


Membership in scientific bodies/juries

Since 2006

  • Scientific delegate AERES (French agency for evaluation), 2009 – 2013

  • Member of the Scientific Board of the Paris Descartes University, since 2012

  • Member of IUF committee, 2009 – 2012

  • Editorial Board of Biology of the Cell, since 2012

  • Member of the ATIP "Molecular Biology" Young investigator Program – international evaluation committee, since 2013

  • Member of the ATIP-Cell and Developmental Biology- Young investigator Program – international evaluation committee, 2008 – 2012

  • Deputy Scientific Director of the Department "Life Sciences" of the CNRS, 2006 – 2007

  • Chair of Scientific committee on Cell and developmental Biology and member of the Scientific Board of ARC (French Association against Cancer), 2006 – 2011

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • Married, two children


Contact

You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here

Testimonials

  1. Read what our members say about AcademiaNet.

No more excuses!

  1. Please download the brochure "No more excuses" and read more about female experts in Europe, and about AcademiaNet.

Similar profiles

  1. Prof. Dr. Anna Akhmanova

    Biological and related sciences Cell Biology, Molecular Biology, Biochemistry, Microscopy

  2. Dr. Chantal Abergel

    Biological and related sciences , Physical sciencesEnvironmental virology, Molecular and structural biology, biochemistry

  3. Prof. Dr. Heike Allgayer

    Biological and related sciences , Health

  4. PhD Mar Albà

    Biological and related sciences Evolution, genomics, bioinformatics