Short CV/Education and training

  • 1986 – 1990
    First examinations in physics at the Darmstadt University of Technology, Germany

  • 1992 – 1996
    Ph.D. thesis in radiation biology and heavy ion physics at the GSI Helmholtzzentrum für Schwerionenforschung (Society for Heavy Ion Research), Darmstadt

  •  
    Training at the University of Paris Decartes, France, and at the Hospital Salpetriere, Paris, France

  • 1996 – 1997
    Certified postgraduate course in medical physics and cancer radiation therapy at the University of Kaiserslautern, Germany

  • 1997 – 1999
    Postdoctoral research fellow at the Centre for Proton Therapy in Orsay, France

Selected publications

  • Tsai, C.J., Ziegler C.: Coupling electron cryomicroscopy and X-ray crystallography to understand secondary active transport. Curr Opin Struct Biol Epub July ahead of print, 2010.

  • Schweikhard, E.S. et al.: Structure and function of the universal stress protein TeaD and its role in regulating the ectoine transporter TeaABC of Halomonas elongata DSM 2581(T). In: Biochemistry 49(10), 2010. pp. 2194-3204.

  • Krämer, R., Ziegler, C.: Regulative interactions of the osmosensing C-terminal domain in the trimeric glycine betaine transporter BetP from Corynebacterium glutamicum. In: Biol. Chem. 390(8), 2009. pp. 685-691.

  • Appel, M. et al.: Conformations of NhaA, the Na+/H+ exchanger from Escherichia coli, in the pH-activated and ion-translocating states. In: J. Mol. Biol. 388(3), 2009. pp. 659-672.

  • Ressl, S. et al.: Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP. In: Nature 458(7234), 2009. pp. 47-52.

  • Kuhlmann, S.I. et al.: 1.55 A structure of the ectoine binding protein TeaA of the osmoregulated TRAP-transporter TeaABC from Halomonas elongata. In: Biochemistry 47(36), 2008. pp. 9475-9485.

  • Kedrov, A. et al.: Examining the Dynamic Energy landscape of an antiporter upon inhibitor binding. In: J. Mol. Biol. 375, 2008. pp. 1258-1266.


Selected projects

  • Development of beam diagnostics for the dosimetry of a 200 MeV proton therapy beam and performance of radiobiological and medical research

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