Short CV/Education and training

  • 1986 – 1990
    First examinations in physics at the Darmstadt University of Technology, Germany

  • 1992 – 1996
    Ph.D. thesis in radiation biology and heavy ion physics at the GSI Helmholtzzentrum für Schwerionenforschung (Society for Heavy Ion Research), Darmstadt

    Training at the University of Paris Decartes, France, and at the Hospital Salpetriere, Paris, France

  • 1996 – 1997
    Certified postgraduate course in medical physics and cancer radiation therapy at the University of Kaiserslautern, Germany

  • 1997 – 1999
    Postdoctoral research fellow at the Centre for Proton Therapy in Orsay, France

Selected publications

  • Tsai, C.J., Ziegler C.: Coupling electron cryomicroscopy and X-ray crystallography to understand secondary active transport. Curr Opin Struct Biol Epub July ahead of print, 2010.

  • Schweikhard, E.S. et al.: Structure and function of the universal stress protein TeaD and its role in regulating the ectoine transporter TeaABC of Halomonas elongata DSM 2581(T). In: Biochemistry 49(10), 2010. pp. 2194-3204.

  • Krämer, R., Ziegler, C.: Regulative interactions of the osmosensing C-terminal domain in the trimeric glycine betaine transporter BetP from Corynebacterium glutamicum. In: Biol. Chem. 390(8), 2009. pp. 685-691.

  • Appel, M. et al.: Conformations of NhaA, the Na+/H+ exchanger from Escherichia coli, in the pH-activated and ion-translocating states. In: J. Mol. Biol. 388(3), 2009. pp. 659-672.

  • Ressl, S. et al.: Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP. In: Nature 458(7234), 2009. pp. 47-52.

  • Kuhlmann, S.I. et al.: 1.55 A structure of the ectoine binding protein TeaA of the osmoregulated TRAP-transporter TeaABC from Halomonas elongata. In: Biochemistry 47(36), 2008. pp. 9475-9485.

  • Kedrov, A. et al.: Examining the Dynamic Energy landscape of an antiporter upon inhibitor binding. In: J. Mol. Biol. 375, 2008. pp. 1258-1266.

Selected projects

  • Development of beam diagnostics for the dosimetry of a 200 MeV proton therapy beam and performance of radiobiological and medical research


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