Short CV/Education and training

  • 1996
    Medical Doctor Degree , School of Medicine, University of Rome, Italy (Summa cum laude)

  • 1996 – 2001
    Graduate Student (Advisor: Dr. Mary C. Weiss), Unité de Génétique de la Différenciation, Pasteur Institute, Paris, France

  • 2001
    Ph.D. Degree, Pasteur Institute-University Paris 6, Paris, France (Summa cum laude)

  • 2002 – 2006
    Postdoctoral Fellow (Advisor: Dr. Ali H. Brivanlou), Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, NY, U.S.A.

  • 2006 – 2008
    Research Associate (Advisor: Dr. Ali H. Brivanlou), Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, NY, U.S.A.

  • Since 2008
    Adjunct Faculty Member, The Rockefeller University, NY, U.S.A.

  • Since 2008
    Group Leader, Max-Delbrueck-Center (MDC), Berlin, Germany

Selected publications

  • Spagnoli FM, Amicone L, Tripodi M, Weiss MC. Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver. J Cell Biol. 1998 143(4):1101-12.

  • Spagnoli FM, Cicchini C, Tripodi M, Weiss MC. Inhibition of MMH cell differentiation by TGF(beta) is abrogated by pre-treatment with the heritable differentiation effector FGF1. J Cell Sci. 2000 113:3639-47.

  • Spagnoli FM, Brivanlou AH. The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification. Dev Biol. 2006 292(2):442-56.

  • Spagnoli FM, Hemmati-Brivanlou A. Guiding embryonic stem cells towards differentiation: lessons from molecular embryology. Curr Opin Genet Dev. 2006

    16(5):469-75. Review.

  • Sapkota G, Alarcón C, Spagnoli FM, Brivanlou AH, Massagué J. Balancing BMP

    signaling through integrated inputs into the Smad1 linker. Mol Cell. 2007 25(3):441-54.

  • Spagnoli FM. From endoderm to pancreas: a multistep journey. Cell Mol Life Sci. 2007 64(18):2378-90. Review.

  • Spagnoli FM, Brivanlou AH. The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. Development. 2008 135(3):451-61.

  • Rosa A, Spagnoli FM, Brivanlou AH. The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection. Dev Cell. 2009 16(4):517-27.

  • Spagnoli FM, Besser D, Benitah SA. Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells. EMBO Rep. 2011 13(1):9-11.


Selected projects

  • Endoderm patterning

  • Pancreas development

  • Liver and Pancreas fate decision

  • Lineage Cell Reprogramming

  • Branching Morphogenesis

Membership in scientific bodies/juries

  • Member of the Society for Developmental Biology, since 2003

  • Member of the New York Academy of Science, since 2002

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