Short CV/Education and training

  • 1989 – 1994
    Studies in Biophysics at Humboldt-University Berlin.

  • 1994 – 1995
    Research, Hoechst AG Frankfurt/M. (now Sanofi-Aventis).

  • 1995 – 2001
    Scientist, Theoretical biophysics, Humboldt-University Berlin.

  • 1997 – 1998
    Stays as guest scientist at the Free University Amsterdam, Netherlands and the National Institute of Bioscience and Human-Technology, Tsukuba, Japan.

  • 2001 – 2003
    Postdoc, Charité Berlin.

  • 2003 – 2005
    Postdoc, GlaxoSmithKline, Medicines Research Centre, Stevenage, UK.

  • 2006 – 2008
    Postdoc, Intern. Research Training Group Berlin-Boston-Kyoto.

  • since 2008
    Group Leader, Max-Delbrueck-Center (MDC) Berlin.

  • 2010 – 2011
    Guest Professor at Humboldt-University, Berlin.

Selected publications

  • K. Baum, A.Z. Politi, B. Kofahl, R. Steuer & J. Wolf (2016), Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations. Plos Comp Biol, 12 (12), e1005298.

  • F. Lorenzin, U. Benary, A. Baluapuri, S. Walz, L. A. Jung, B. von Eyß, C. Kisker, J. Wolf, M. Eilers & E. Wolf (2016), Different promoter affinities account for specificity in MYC-dependent gene regulation, elife. 2016; 5.

  • Y. Murakawa, M. Hinz, J. Mothes, A. Schuetz, M. Uhl, E. Wyler, T. Yasuda, G. Mastrobuoni, C.C. Friedel, L. Doelken, S. Kempa, M. Schmidt-Supprian, N. Bluethgen, R. Backofen, U. Heinemann, J Wolf, C. Scheidereit & M. Landthaler (2015), RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-{kappa}B pathway. Nature Comm. 6: 7367.

  • J. Mothes, D. Busse, B. Kofahl, J. Wolf (2015). Sources of dynamic variability in the NF-κB signal transduction: A mechanistic model, Bioessays 37, 457.

  • U. Benary, B. Kofahl; A. Hecht & J. Wolf (2015), Mathematical Modelling suggests Differential Impact of β-TrCP Paralogues on Wnt/β-catenin Signalling Dynamics, FEBS J. 282, 1080.

  • Z.B. Yilmaz, B. Kofahl, P. Beaudette, K. Baum, F. Weih, J. Wolf, G. Dittmar & C. Scheidereit (2014), Quantitative Dissection and Modeling of the NF-κB p100-p105 Module reveals interdependent precursor proteolysis, Cell Reports 9, 1756.

  • B. Schwanhäusser, J. Wolf, M. Selbach & D. Busse (2013), Synthesis and degradation jointly determine the responsiveness of the cellular proteome, Bioessays 35(7), 597.

  • U. Benary*, B. Kofahl*, A. Hecht & J. Wolf (2013), Modelling Wnt/β-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions, Front. Physiol. 4:21 (* equal contributions).

  • V. Schmidt, K. Baum, A. Lao, K. Rateitschak, Y. Schmitz, A. Teichmann, B. Wiesner, C.M. Petersen, A. Nykjaer, J. Wolf, O. Wolkenhauer & T.E. Willnow (2012), Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease, EMBO Journal 31(1), 187.

  • B. Schwanhäusser, D. Busse, N. Li, G. Dittmar, J. Schuchhardt, J. Wolf*, W. Chen* & M. Selbach* (2011), Genome-wide parallel quantification of mRNA and protein levels and turnover in mammalian cells. Nature 473, 337 (* corresponding authors).

  • J. Schütze*, T. Mair*, M.J.B. Hauser, M. Falcke & J. Wolf (2011), Metabolic synchronisation by travelling waves in yeast cell layers, Biophys. J. 100 (4), 809 (* equal contribution).

  • B. Kofahl & J. Wolf (2010), Mathematical modelling of Wnt/ β-catenin signalling. Biochem. Soc. Trans. 38, 1281.


Membership in scientific bodies/juries

  • Elected member of the MDC Supervisory Board, since 2015.

  • Elected member of the MDC Board of Trustees, 2013 – 2015.

  • Member of several search committees (Professorships, Junior Group Leader Positions).

  • PI in the International Helmholtz Research School ‘Frontiers in Cell Signaling and Gene Regulation’ (SignGene), since 2012.

  • Extended Faculty member of the Berlin School of Integrative Oncology (BSIO), since 2012.

  • PI in the Graduate School ‘Computational Systems Biology’, since 2011.

Additional qualifications

  • 2012 – 2014 Management Training ‘Helmholtz Akademie für Führungskräfte’


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