Short CV/Education and training

  • 2002 – 2006
    PhD and early post-doctoral career spent in Australia (PhD, Melbourne) and London (Post-Doc, UCL) with a focus on cancer immunotherapy

  • 2006
    The Gambia, research objectived changed to tuberculosis/infectious diseases

  • 2011
    Honorary Assoc. Professor, Imperial College, London, UK

Selected publications

  • Heslop R, Bojang AL, Jarju S, Mendy J, Mulwa S, Secka O, Mendy FS, Owolabi O, Kampmann B, Sutherland JS. Changes in host cytokine patterns of TB patients with different bacterial loads detected using 16S rRNA analysis. Plos One. 2016; 11: e0168272

  • Zak DE, Penn-Nicholson A, Scriba TJ, Thompson E, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Hussey GD, Abrahams D, Kafaar F, Hawkridge T, Verver S, Hughes EJ, Ota M, Sutherland J, Howe R, Dockrell HM, Boom WH, Thiel B, Ottenhoff TH, Mayanja-Kizza H, Crampin AC, Downing K, Hatherill M, Valvo J, Shankar S, Parida SK, Kaufmann SH, Walzl G, Aderem A, Hanekom WA; ACS and GC6-74 cohort study groups. A blood RNA signature for tuberculosis disease risk: a prospective cohort study. Lancet. 2016; 387: 2312-22

  • Ota MOC, Mendy JF, Donkor S, Togun T, Daramy M, Gomez MP, Chegou NN, Sillah AK, Owolabi O, Kampmann B, Walzl G, Sutherland JS. Rapid diagnosis of tuberculosis using ex vivo host biomarkers in sputum. Eur. Respir. J. 2014; 44: 254-257.

  • Elliott TO, Owolabi O, Donkor S, Kampmann B, Hill PC, Ottenhoff TH, Haks MC, Kaufmann SH, Maertzdorf J, Sutherland JS. Dysregulation of Apoptosis Is a Risk Factor for Tuberculosis Disease Progression. J Infect Dis. 2015; 212: 1469-1479.

  • Sutherland JS, Adetifa IM, Hill PC, Adegbola RA, Ota MO. Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease. Eur J Immunol. 2009; 39: 723-729.

  • Sutherland JS, Young JM, Peterson KL, Sanneh B, Whittle HC, Rowland-Jones SL, Adegbola RA, Jaye A, Ota MO. Polyfunctional CD4+ and CD8+ T cell responses to tuberculosis antigens in HIV-1-infected patients before and after anti-retroviral treatment. J Immunol. 2010; 184: 6537-6544.

  • Wilson H, de Jong BC, Peterson K, Jaye A, Kampmann B, Ota MOC, Sutherland JS. Skewing of the CD4+ T cell pool towards mono-functional antigen-specific responses in patients with immune reconstitution inflammatory syndrome in The Gambia. Clin Infect Dis. 2013; 57: 594-603.

  • Sutherland JS et al. Differential gene expression of activating Fcγ receptor classifies active TB regardless of HIV status or ethnicity. Clin Microbiol Infect. 2014; 20: O230-8

  • Coscolla M, Copin R, Sutherland J, Gehre F, de Jong B, Owolabi O, Mbayo G, Giardina F, Ernst JD, Gagneux S. M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens. Cell Host Microbe. 2015; 18: 538-548

  • Sutherland JS, Mendy J, Gindeh A, Walzl G, Togun T, Owolabi O, Donkor S, Ota MO, Kon Fat ET, Ottenhoff TH, Geluk A, Corstjens PL. Use of lateral flow assays to determine IP-10 and CCL4 levels in pleural effusions and whole blood for TB diagnosis. Tuberculosis (Edinb). 2016; 96: 31-36.



Complete list of publications

Selected projects

  • TB-SEQUEL

    This project involves understanding the pathogenesis and risk factors of long-term pulmonary sequelae defining the individual outcome and public health impact of TB disease.

  • SCREEN-TB

    This is a multi-site study aiming to validate a biomarker signature for development of a point-of-care screening test for TB using finger-prick blood.

  • TBVAC2020

    The goal of this project is to define new vaccine candidates for TB. My focus is understanding early protective immunity to Mtb infection.

  • GC6-2013: Biomarkers for TB consortium

    The goal of this project is to analyse samples from incident cases and controls to define correlates of risk for TB.

  • MRC(UK) TB case-contact platform

    This funding allows analysis and sample collection from TB patients and their exposed contacts to define host-pathogen interactions and provide a basis for vaccine and diagnostic studies.

Membership in scientific bodies/juries

Memberships

  • Associate Editor, BMC ID, 2017

  • Site assessment panel for Wellcome Trust, 2015

  • Member, Scientific Co-ordinating Committee, MRCG, since 2013

  • Steering committee member for GC6, since 2013

  • Member, Higher Degrees Committee, Open University, since 2011

Speaking Engagements

  • Invited speaker, TB2016, Durban, South Africa, 2016

  • Invited Speaker, Euroscion conference, London, UK, 2013

  • Invited Speaker, ITM, Pathogen-host, Dec, Antwerp, Belgium, 2012

Sholarships, Grants

  • GC6 small project grant, 2012

  • Keystone NIH scholarship, 2009

  • The Alfred small project grant, 1999

  • The Alfred Postgraduate Research Scholarship, 1998

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