Short CV/Education and training

  • 1997 – 2002
    Studied biology at the University of Osnabrück, Germany, toward the Diplom degree

  • 2002 – 2003
    Research associate at the University of Osnabrück

  • 2004 – 2007
    External doctoral student working at the Leibniz Institute of Arteriosclerosis Research in Münster, Germany (Dr. rer. nat. from the University of Osnabrück)

  • 2008 – 2010
    Postdoc at the Institute of Musculoskeletal Medicine, University Hospital Münster

  • 2010 – 2011
    German Research Foundation (DFG) research fellowship to the William Harvey Research Institute, Barts and the London School of Dentistry and Medicine, London, UK

  • 2012
    DFG return grant to the Institute of Musculoskeletal Medicine, University Hospital Münster

  • 2013
    Head of a DFG Emmy Noether junior research group at the Institute of Musculoskeletal Medicine, University Hospital Münster

Selected publications

  • Lindemann O, Umlauf D, Frank S, Schimmelpfennig S, Bertrand J, Pap T, Hanley PJ, Fabian A, Dietrich A, Schwab A (2013) TRPC6 regulates CXCR2-mediated chemotaxis of murine neutrophils Journal of Immunology, J Immunol., 1;190(11):5496-505.

  • Frank S., Peters M.A., Wehmeyer C., Strietholt S., Koers-Wunrau C., Bertrand J., Heitzmann M., Hillmann A., Sherwood J., Seyfert C., Gay S., Pap T. Regulation of matrix metalloproteinase-3 and -13 by SUMO-2/3 through the transcription factor NF-kB. Ann Rheum Dis (2013) in press.

  • Schmidt-Lauber C., Pap T., Fischer M., Victor M., Heitzmann M., Hansen U., Fobker M., Pavenstädt H., Sindic A., Edemir B., Harrach S., Köllmann K., Schlatter E., Bertrand J. and Ciarimboli G. Importance of transporters and their pathology-induced regulation for drug delivery into RA synovial fibroblasts at the example of the triad Imatinib. PLos ONE, 2012;7(12):e52247

  • Bertrand J.*, Stange R.*, Echtermeyer F., Hidding H., Godmann L., Nalesso G., Pap T., Bruckner P., Dell'Accio F., Dreier R. Regulation of embryonic bone development and fracture repair by Syndecan-4. Arthritis Rheum., 2012 Dec 11. * both authors contributed equally

  • Fabian A, Bertrand J, Lindemann O, Pap T, Schwab A. Transient receptor potential canonical channel 1 impacts on mechanosignaling during cell migration. Pflugers Arch. 2012 Oct 112012 Dec;464(6):623-30.

  • Bertrand J.*, Nitschke Y.*, Fuerst M., Ruether W., Hermann S., Schäfers M., Nalesso G., Sherwood J., Rutsch F., Dell?Accio F. and Pap T. Decreased levels of Nucleotide Pyrophosphatase Phosphodiesterase NPP1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. Ann Rheum Dis 2012;71:1249-1253. * both authors contributed equally

  • Nalesso G., Sherwood J., Bertrand J., Pap T., Ramachandran M., De Bari C., Pitzalis C.,dell'Accio F. WNT-3A modulates articular chondrocyte phenotype by activating both canonical and non canonical pathways. J Cell Biol. 2011 May 2;193(3):551-64.

  • Echtermeyer F. *, Bertrand J.*, Dreier R., Neugebauer K., Lee YJ, Song YW, Fürst M., Herzog C. and Pap T. Syndecan-4 regulates enchondral ossification and cartilage degradation in osteoarthritis. Nat Med. 2009 Sep;15(9):1072-6. * both authors contributed equally

  • Fuerst M.*, Bertrand J.*, Lammers L., Dreier R., Echtermeyer F., Nitschke Y., Rutsch F., Schäfer F., Niggemeyer O., Steinhagen J., Dreimann M., Pap T. and Rüther W. Prevalence and structure of calcium crystals in advanced osteoarthritis of the knee. Arthritis Rheum. 2009 Sep;60(9):2694-703. * both authors contributed equally


Selected projects

  • German Research Foundation (DFG) return grant BE4328/4-1: Involvement of syndecan-4 in wnt signalling in cartilage biology, 11/2011 – 04/2012

  • DFG research grant BE4328/3-1: Involvement of syndecan-4 in wnt signalling in cartilage biology, 11/2010 – 11/2011

  • Medical Faculty Münster's Innovative Medical Research (IMF) project BE121009: Treatment of fibrosing and inflammatory diseases with tyrosine-kinase

    inhibitors: Modulation of the absorption of these agents by means of pathology-associated changes and genetic alterations in organic cation transporters, 2011 – 2012 (+ 2013)

Membership in scientific bodies/juries

  • Reviewer for the French National Research Agency

  • Ad hoc reviewer for the following scientific journals: Arthritis Research and Therapy, Annals of the Rheumatic Diseases, British Journal of Pharmacology, Calcified Tissue International, Osteoarthritis and Cartilage, Pakistan Veterinary Journal, Zeitschrift für Rheumatologie (Journal of Rheumatology).

Additional qualifications

  • 2012 – 2013: Management course "Young Leaders in Science" (Schering Foundation)

  • 2009: Teacher training course "Plenary didactics" (UKM)

  • 2008: Seminar for project heads: "Genetic engineering facilities" (University Hospital Münster (UKM), Germany)

  • 2008: Course in the area of laboratory animal science (UKM)

  • 2000: Public speaking course for female students: "Communication – Self-confidence"


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