Short CV/Education and training

  • 2001 – 2004
    PhD studies University Paris VI, France

  • 2005 – 2008
    Post-doc fellow, NIH, USA

  • 2008 – 2015
    Senior Researcher, Institut Cochin, Paris, France

  • 2015
    Senior Researcher, Cancer Research Center, Nantes, France

Selected publications

  • Treps L, Edmond S, Harford-Wright E, Galan-Moya EM, Schmitt A, Azzi S, Citerne A, Bidere N, Ricard D, Gavard J. Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma. Oncogene. In press.

  • Azzi S, Smith SS, Dwyer J, Leclair HM, Alexia C, Hebda JK, Dupin N, Bidere N, Gavard J. YGLF motif in the Kaposi Sarcoma Herpes Virus G protein coupled receptor adjusts NF-κB activation and paracrine actions. Oncogene. 2014; 33(49): 5609-18.

  • Le Guelte A, Galan-Moya EM, Dwyer J, Treps L, Kettler G, Hebda JK, Dubois S, Auffray C, Chneiweiss H, Bidere N, Gavard J. Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation. J Cell Sci. 2012; 125: 4137-46.

  • Galan-Moya EM, Le Guelte A, Lima Fernandes E, Thirant C, Dwyer J, Bidere N, Couraud PO, Scott MG, Junier MP, Chneiweiss H, Gavard J. Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway. EMBO Rep. 2011; 12(5): 470-6.

  • Dwyer J, Le Guelte A, Galan Moya EM, Sumbal M, Carlotti A, Douguet L, Gutkind JS, Grange PA, Dupin N, Gavard J. Remodeling of VE-cadherin junctions by the human herpes virus 8 G-protein coupled receptor. Oncogene. 2011; 30(2): 190-200.

  • Gavard J, Patel V, Gutkind JS. Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia. Dev Cell. 2008; 14(1): 25-36.

  • Gavard J, Gutkind JS. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat Cell Biol. 2006; 8(11): 1223-34.

Selected projects

  • Cellular and molecular interactions in glioblastoma vascular niche

  • Fundamental mechanisms of vascular permeability/integrity

Membership in scientific bodies/juries

  • CNRS 24, Physiology, Ageing, Cancer

  • French National Cancer Institute INCA

  • Fondation de France Cancer Committee

Soft Skills/Other activities and achievements

Additional interests

  • Communicating science: twitter @LabSoap

Other activities and achievements/family

  • Mother of two beautiful and awesome kids, born 2009 and 2013.


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