Prof. Dr. Amparo Acker-Palmer
Biological and related sciences , HealthCell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology
Biological and related sciences , Engineering and engineering trades , Health
Bone biomechanics, mechanobiology, bone cell biology, finite element analysis, tissue regeneration
Mechanical characterisation of biological tissues
Bone cell biology
Mechanobiology
Bone tissue regeneration in vitro
Finite element modelling
Adaptive modelling of biological processes
Awarded the "Bone and Joint Decade" New Investigator Research Award (NIRA) at the 52nd Annual Meeting of the Orthopaedic Research Society, 2006
Awarded an American Society for Bone and Mineral Research Harold B. Frost Young Investigator Award at the 35th International Sun Valley Workshop on Skeletal Biology, Idaho, August 2005
Finalist for Engineers of Ireland (IEI) Biomedical Engineering Medal, 2004
Awarded the first prize for student award at the 13th Meeting of the European Society of Biomechanics, Wraclow, Poland, 2002
Exam prizewinner in 1998, 1999, 2000 from NUI Galway, Ireland
Appointed under Science Foundation Ireland (SFI) Stokes Programme as Lecturer in Biomechanics
Theme leader (Mechanobiology) for 17th European Society of Biomechanics, to be held in 2010.
Invited Chair for the "Mechanotransduction and Fracture Healing" session at the European Society of Biomechanics Finite Element Modelling in Biomechanics and Mechanobiology Workshop in 2007.
Invited to write "Bone as a material" chapter for "Comprehensive Biomaterials" (P. Ducheyne, K. Healy, D. Hutmacher, J. Kirkpatrick, Eds.) in 2012 by Elsevier
Invited speaker at Ortoreuma 2005: International Conference on Bone and Joint Aging, Milan, Italy, September 2005. Bone tissue material properties are altered during osteoporosis
Invited seminar at the City College of New York, United States, 2005: Biomechanical origins of Osteoporosis
Invited seminar at the Trinity Centre for Bioengineering, Ireland, 2006: The contribution of bone extracellular matrix to osteocyte function in vivo and in vitro
Invited speaker at the Microdamage symposium at the 14th Meeting of the European Society of Biomechanics, The Netherlands, 2004
Invited speaker at the Orthobiologics seminar series, Regenerative Medicine Institute (REMEDI), NUI Galway, Ireland, October 2009.
English
Birmingham, E., Niebur, G.L., McHugh, P.E., Shaw G., Barry F.P., McNamara, L.M. Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche. European Cells and Materials, January 2012. 23: 13-27.
Brennan, O., O'Brien, F.J., McNamara, L.M. Estrogen Plus Estrogen Receptor Antagonists Alter Mineral Production by Osteoblasts in vitro. Horm Metab Res 2012. 44(01): 47-53.
Brennan, M., Gleeson, J.P., Browne, M., O?Brien, F.J., Thurner, P.J., McNamara, L. Site Specific Increase in Heterogeneity of Trabecular Bone Tissue Mineral during Estrogen Deficiency. European Cells and Materials. 2011 May 15; 21:396-406.
Brennan O, Kennedy OD, Lee TC, Rackard SM, O'Brien FJ, McNamara LM. The effects of estrogen deficiency and bisphosphonate treatment on tissue mineralisation and stiffness in an ovine model of osteoporosis. J Biomech. 2011 3;44(3):386-90
McNamara, LM, Perspective on Postmenopausal Osteoporosis: Establishing an interdisciplinary understanding of the sequence of events from the molecular level to whole bone fractures, J R Soc Interface. 2010 Mar 6;7(44):353-72.
McNamara, LM, Majeska, RJ, Weinbaum, S, Friedrich, V, Schaffler, MB, Attachment of osteocyte cell processes to the bone matrix, The Anatomical Record; 2009; 292(3):355-63
Wang Y, McNamara LM, Schaffler MB, Weinbaum S. Strain amplification and integrin based signaling in osteocytes.J Musculoskelet Neuronal Interact. 2008; 8(4):332-4
Mulvihill, BM, McNamara LM, Prendergast, PJ. Loss of trabeculae in osteoporotic cancellous bone by biomechanical means, J R Soc Interface. 2008; 6; 5(27):1243-53.
Wang, Y, McNamara, LM, Schaffler, MB, Weinbaum, S, A Model for the Role of Integrins in Flow Induced Mechanotransduction in Osteocytes, Proc Natl Acad Sci USA. 2007; 2; 104(40):15941-6
McNamara, LM, Prendergast, PJ, 2007, Bone remodelling algorithms incorporating both strain and microdamage stimuli, J Biomech.; 40(6):1381-91
Mulvihill, BM, McNamara LM, Prendergast, PJ, The effect of patient-specific bone remodeling rates on remodelling/repair in trabecular bone, III International congress on computational bioengineering
Mulvihill, BM, McNamara LM, Prendergast, PJ, Increases in the elastic modulus of trabecular bone tissue leads to more rapid perforation of trabeculae in osteoporotic bone, Proceedings of the ASME Summer Bioengineering Conference
McNamara, LM, Lyons, CG, Ederveen, AH, Weinans, H, Price, CJ, Schaffler, MB, Prendergast, PJ, Strength of cancellous bone trabecular tissue from normal, ovarectomized and drug-treated rats over the course of ageing, BONE, 2006 Aug; 39 (2): 392 – 400
McNamara, LM, Van der Linden, JC, Weinans, H, Prendergast, PJ, Stress-concentrating effect of resorption lacunae in trabecular bone, Journal of Biomechanics, 2006;39(4):734-41
McNamara, LM, Prendergast, PJ, Schaffler, MB, Bone tissue material properties are altered during Osteoporosis, J Musculoskelet Neuronal Interact, 2005; 5(4):342-3
McNamara, LM, Prendergast, PJ, Perforation of cancellous bone trabeculae by damage-stimulated remodelling at resorption pits: a computational analysis, European Journal of Morphology, Vol. 42, No. 1/2, 99-109, 2005
€ 1,499,910- European Research Council Starting Independent Researcher Grant entitled Frontier research in bone mechanobiology during normal physiology, disease and for tissue regeneration
€ 18,794 Science Foundation Ireland (SFI) Short Term Travel Fellowship (STTF) (Outgoing) for a collaborative research project with Professor Ajit Yoganathan at Georgia Tech University entitled The Effect of Asymmetric Deployment on Leaflet Fatigue Durability in Transcatheter Aortic Heart Valves
€ 19,000 Science Foundation Ireland (SFI) Short Term Travel Fellowship (STTF) (Incoming) for a collaborative research project with Professor Glen Niebur at Notre Dame University entitled The Effect of Asymmetric Deployment on Leaflet Fatigue Durability in Transcatheter Aortic Heart Valves
€ 8,500 Millennium fund grant, National University of Ireland, Galway
€ 313,311- Health Research Board General Research Grant entitled Bone tissue mineralization process during osteoporosis, 2007-2010
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Biological and related sciences , HealthCell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology
Biological and related sciences , Physical sciencesEnvironmental virology, Molecular and structural biology, biochemistry
Biological and related sciences , Physical sciencesBioelectrochemistry, Synthetic Biology, Chemical Biology
Biological and related sciences Evolutionary biology, Animal behaviour, Gender studies, Science studies