Short CV/Education and training

  • 1993 – 1995
    M.Sc., York University, Toronto, Canada

  • 1995 – 1999
    Ph.D. with Distinction, York University, Toronto, Canada

  • 1999 – 2005
    Postdoctoral Research Fellow, Cancer Research UK, Clare Hall Laboratories

  • 2005 – 2011
    Junior Group Leader, Telomere and Genome Stability Group, The CR-UK/MRC Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford

  • Since 2011
    Senior Group Leader, Telomere and Genome Stability Group, The CR-UK/MRC Gray Institute of Radiation Oncology and Biology, Department of Oncology, University of Oxford

Selected publications

  • *Carlos AR*, Escandell J*, Kotsantis P, Suwaki N, Bouwman P, Badie S, Folio C, Benitez J, Gomez-Lopez G, Pisano D, Jonkers J and Tarsounas M. 2013. ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets. Nat Commun. 4: 697; *equal contribution.

  • Thanasoula M, Escandell J, Suwaki N and Tarsounas M. 2012. ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres. EMBO J 31:3398-3410.

  • Thanasoula M, Escandell J, Martinez P, Badie S, Munoz P, Blasco MA and Tarsounas M. 2010. p53 prevents entry into mitosis with uncapped telomeres. Current Biol 20:521-526.

  • Badie S*, Escandell J*, Bowmann P*, Carlos AR, Thanasoula M, Gallardo MM, Suram A, Jaco I, Benitez J, Herbig U, Blasco MA, Jonkers J and Tarsounas M. 2010. BRCA2 acts as RAD51 loader to facilitate telomere replication and capping. Nat Struct Mol Biol 17: 1461-1469. *equal contribution.

  • Bouwman P*, Aly A*, Escandell JM*, Pieterse M, Bartkova J, van der Gulden H, Hiddingh S, Thanasoula M, Kulkarni A, Yang Q, Haffty B, Tommiska J, Blomqvist C, Drapkin R, Adams DJ, Nevanlinna H, Bartek J, *Tarsounas M*, *Ganesan S* and *Jonkers J*. 2010. 53BP1 loss abrogates DNA damage responses in Brca1-null cells and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 17:688-695. *equal contribution and equal corresponding authorship.

  • Martinez P, Thanasoula M, Carlos AR, Gomez G, Tejera A, Schoeftner S, Dominguez O, Pisano DG, Tarsounas M and Blasco M. 2010. Role of mammalian RAP1 in TERT recruitment and telomere maintenance, subtelomeric gene silencing and general transcriptional regulation. Nat Cell Biol 12:768-780.

  • Tejera AM*, Stagno d´Alcontres M*, Thanasoula M, Martinez P, Liao C, Tarsounas M and Blasco MA. 2010. TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Developmental Cell 18:775-789. *equal contribution.

  • Badie S, Liao C, Thanasoula M, Barber P, Hill M and Tarsounas M. 2009. RAD51C facilitates checkpoint signalling by promoting CHK2 phosphorylation. J Cell Biology 185:587-600.

Complete list of publications


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