Short CV/Education and training

  • 1998 – 1999
    Undergraduate student (Masters thesis: Regulation of endocytosis by Ca2+ and IP3), Department of Biology, University of Jyväskylä, Finland with Dr. Varpu Marjomäki

  • 1999 – 2003
    Graduate student (PhD thesis: Regulation of actin dynamics in animal cells: the role of ADF/cofilin and twinfilin), Institute of Biotechnology, University of Helsinki, Finland with Dr. Pekka Lappalainen

  • 2003
    Post doctoral fellow: Cell biological significance of the three mouse Scar proteins, School of Biosciences, University of Birmingham, UK with Prof. Laura Machesky

  • 2003 – 2007
    Post doctoral fellow: regulation of the localization and activity of the SRF cofactor MAL by actin, Transcription laboratory, Cancer Research UK, London with Dr Richard Treisman

  • 2007
    Group leader, Institute of Biotechnology, Helsinki, Finland

  • 2007
    Docent in Cell Biology, speciality live-cell imaging

  • 2008 – 2014
    Research fellow, Academy of Finland

  • 2010
    Scientific advisor to the Light Microscopy Unit (LMU), Institute of Biotechnology

Selected publications

  • Grosse R, Vartiainen MK (2013). To be or not to be assembled: progressing into nuclear actin filaments. Nature Reviews Molecular Cell Biology Nov;14(11):693-7.

  • Ho CY, Jaalouk DE, Vartiainen MK, Lammerding, J. (2013). Lamin A/C and emerin regulate MKL1/SRF activity by modulating actin dynamics. Nature 497(7450):507-11

  • Huet G, Rajakylä EK, Viita T, Skarp KPS, Crivaro M, Dopie J, Vartiainen MK. Actin-regulated feedback loop based on Phactr4, PP1 and cofilin maintains actin monomer homeostasis J Cell Sci 126(Pt 2):497-507

  • Dopie J, Skarp KP, Rajakylä EK, Tanhuanpää K, Vartiainen MK. Active maintenance of Nuclear actin by Importin 9 supports Transcription. PNAS (2012) Feb 28; 109(9):E544-52. Epub 2012 Feb 9

  • Vartiainen MK*, Guettler S*, Larijani B, Treisman R (2007). Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL. Science Jun 22; 316 (5832) 1749-52 * equal contribution



Complete list of publications

Selected projects

  • ERC Starting grant: Actin as the master organizer of nuclear structure and function

  • Academy of Finland: Nuclear actin in transcription: from mechanisms to physiological relevance

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • Mother of two boys, born 2010 and 2013


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