Short CV/Education and training

  • 2003
    Master's student at the Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

  • 2003 – 2006
    PhD student with funding from the German Research Foundation (DFG) at the Department of Human Genetics, Ulm University, Germany

  • 2006 – 2007
    Postdoc at the Department of Molecular Genetics, Heidelberg, Germany; position supported by the German Cancer Research Centre (DKFZ)

  • 2008 – 2010
    Postdoc with support from the Faculty of Medicine, Department of Paediatric Oncology, Haematology and Immunology of Heidelberg University

  • since 2010
    Group leader, Department for Molecular Genetics, DKFZ, Heidelberg

Selected publications

  • Goidts, V. et al.: Segmental duplication associated with the human specific inversion of chromosome 18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates. In: Hum. Genet. 115, 2004. S. 116-122.

  • Goidts, V. et al.: Independent intrachromosomal recombination events underlie the pericentric inversion of chimpanzee and gorilla chromosomes homologous to human chromosome 16. In: Genome Res. 15, 2005. S. 1232-1242.

  • Goidts, V. et al.: Identification of large-scale human-specific copy-number variations by inter-species array comparative genomic hybridization. In: Hum. Genet. 119, 2006. S. 185-198.

  • Szamalek, J., Goidts, V. et al.: Characterization of the human specific pericentric inversion that discriminates human chromosome 1 from its homologous in great apes. In: Hum. Genet. 120, 2006. S. 126-138.

  • Goidts, V. et al.: Complex patterns of copy number variation at sites of segmental duplications: an important category of structural variation in the human genome. In: Hum. Genet. 120, 2006. S. 270-284.

  • Campos, B. et al.: Differentiation therapy exerts antitumor effects on stem-like glioma cells. In: Clin. Cancer Res. 16, 2010. S. 2715-2728.

  • Goidts, V. et al.: The bifunctional gene PFKFB4 and aerobic glycolysis are essential for the survival of brain tumor initiating cells. In: Oncogene 31, 2012. S.3235-3243.

  • Nakata S. et al.: LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells. In: Brain Pathol. 2012


Selected projects

  • Identification of new potential therapeutic targets of brain tumour-initiating cells by loss-of-function screens

  • Study of the importance of metabolism for the survival of brain tumour-initiating cells

Additional qualifications

  • Helmholtz-Mentoring-Program for young women working at the Helmholtz Association "Taking the Lead" ("In Führung gehen"), Berlin, Germany, 2010.

  • Teaching and Learning I + II: professional development module of the Baden-Württemberg Certificate for Teaching in Higher Education, Academy for Continuing Scientific Education at the Pädagogische Hochschule Heidelberg (University of Education), 2010

  • 18th session in Medical Genetics, Bologna University, Italy. Received 30 hours from the European Union of Medical Specialists, 2005

  • 16th International Summer School of Epidemiology. Specialisation in the epidemiology of infectious inflammatory diseases and clinical problems, 2005

  • 15th International Summer School of Epidemiology. Specialisation in genetic epidemiology and cancer epidemiology, 2004

  • Erasmus exchange programme with the University of Uppsala, Sweden; specialisation in developmental biology and molecular biology, 2001 – 2002


Soft Skills/Other activities and achievements

Other activities and achievements/family

  • Married with two children (born in June 2008 and July 2011).


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News

  1. Targeted Attack Against Brain Tumors

    In a study managed by Dr. Violaine Goidts, researchers at the German Cancer Research Center have discovered an enzyme that drives the growth of glioblastomas, the most aggressive brain tumors. Agents that block this enzyme may be used to halt the growth of these tumors.