Short CV/Education and training

  • 1992 – 1997
    Studium der Biologie an der Justus-Liebig-Universität Gießen und der Universität zu Köln

  • 1996 – 1997
    Diplomstudium und Diplomarbeit am Max-Planck-Institut für molekulare Physiologie in Dortmund

  • 1997 – 2000
    Dissertation / PhD thesis am Max-Planck-Institut für molekulare Physiologie in Dortmund

  • 2000 – 2001
    Postdoctoral fellow am Max-Planck-Institut für molekulare Physiologie in Dortmund

  • 2001 – 2004
    Postdoctoral fellow am National Institute for Medical Research London, UK

Selected publications

  • Rufer, A.C. et al.: Isoform-selective interaction of the adaptor protein Tks5/FISH with Sos1 and dynamins. In: J Mol Biol 390, 2009. S. 939-950.

  • Kintscher C and Groemping Y (2009). Characterisation of the nucleotide exchange factor ITSN1L: Evidence for a kinetic discrimination of GEF stimulated nucleotide release from Cdc42. J Mol Biol, 387 (2):270-283.

  • Rumpf, J. et al.: Structure of the Eps15-stonin2 complex provides a molecular explanation for EH domain ligand specificity. In: EMBO J. 27, 2008. S. 558-569.

  • Groemping Y and Rittinger K (2005). Activation and assembly of the NADPH oxidase: a structural perspective. Biochem J 386: 401-416.

  • Groemping, Y. et al.: Molecular basis of phosphorylation-induced activation of the NADPH oxidase. In: Cell 113, 2003. S. 343-355.

  • Groemping, Y., Reinstein, J.: Folding properties of the nucleotide exchange factor GrpE from Thermus thermophilus: GrpE is a thermosensor that mediates heat shock response. In: J Mol Biol 314, 2001. S. 167-178.


Selected projects

  • Specificity of modular domains involved in endocytosis and signal transduction pathways

  • Organisation of the actin cytoskeleton via Rho GTPases and their regulators

  • Cooperative binding effects of EH and SH3 domains

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