Short CV/Education and training

  • 1998 – 2003
    studied Chemistry (major Nuclear Chemistry) at the Johannes Gutenberg-University Mainz, Germany

  • 2001 – 2002
    Term abroad at the Nagoya University, Japan

  • 2003
    Diploma in Radiopharmaceutical Chemistry at the Johannes Gutenberg-University Mainz, Germany

  • 2004
    Research Associate at the Johannes Gutenberg-University Mainz, Germany

  • 2005 – 2007
    PhD at the German Cancer Research Center / Ruprecht Karls-University Heidelberg, Germany

  • 2007 – 2009
    PostDoc at the McGill University, Montreal, Canada

  • 2010 – 2013
    Junior Researcher Group Leader at the Ludwig Maximilians-University (LMU) Munich, Germany and Ruprecht Karls-University Heidelberg, Germany

  • 2011
    Priv.Doz. (Associate Professor), Experimental Nuclear Medicine, Ludwig Maximilians-University (LMU) Munich

  • since 2013
    Group Leader for Biomedical Chemistry at the Ruprecht Karls-University Heidelberg, Germany

Selected publications

  • Wängler C, Niedermoser S, Chin J, Orchovski K, Schirrmacher E, Jurkschat K, Iovkova-Berends L, Kostikov AP, Schirrmacher R, Wängler B (2012) One-step 18F-labeling of peptides for Positron Emission Tomography imaging using the SiFA methodology. Nature Protocols 7(11), 1946-1955.

  • Wängler C, Schäfer M, Schirrmacher R, Bartenstein P, Wängler B (2011) DOTA derivatives for site-specific biomolecule-modification via click chemistry: Synthesis and comparison of reaction characteristics. Bioorganic & Medicinal Chemistry 19, 3864-3874.

  • Schirrmacher R, Lucas P, Schirrmacher E, Wängler B, Wängler C (2011) Alpha selective epoxide opening with 18F-: Synthesis of 4-(3-[18F]fluoro-2-hydroxypropoxy)benzaldehyde ([18F]FPB) for peptide labeling. Tetrahedron Letters 52, 1973-1976.

  • Wängler C, Wängler B, Lehner S, Elsner A, Todica A, Hacker M, Bartenstein P, Schirrmacher R (2011) Protein based imaging agents for in vivo Positron-Emission-Tomography – a universally applicable gallium-68 labeling technique. Journal of Nuclear Medicine 52, 586-591.

  • Wängler C, Nada D, Höfner G, Maschauer S, Wängler B, Schneider S, Schirrmacher E, Wanner KT, Schirrmacher R, Prante O (2011) In vitro and initial in vivo evaluation of 68Ga-labeled transferrin receptor (TfR) binding peptides as potential carriers for enhanced drug transport into TfR expressing cells. Molecular Imaging and Biology 13, 332-341.

  • Wängler C, Waser B, Alke A, Iovkova L, Buchholz H-G, Niedermoser S, Jurkschat K, Fottner C, Bartenstein P, Schirrmacher R, Reubi J-C, Wester H-J, Wängler B (2010) 18F one-step labeling of carbohydrate-conjugated octreotate-derivatives containing a Silicon-Fluoride-Acceptor (SiFA): In vitro and in vivo evaluation as tumor imaging agents for Positron Emission Tomography (PET). Bioconjugate Chemistry 21, 2289-2296.

  • Wängler C, Maschauer S, Prante O, Schirrmacher R, Bartenstein P, Eisenhut M, Wängler B (2010) RGD-multimerization for improved molecular imaging properties: Chemical and biological limitations. ChemBioChem 11(15), 2168-2181.

  • Wängler C, Schirrmacher R, Bartenstein P, Wängler B (2009) Simple and convenient radiolabeling of proteins using a prelabeling-approach with thiol-DOTA. Bioorganic & Medicinal Chemistry Letters 19, 1926-1929.

  • Wängler C, Moldenhauer G, Knapp E-M, Beijer B, Schnölzer M, Wängler B, Eisenhut M, Haberkorn U, Mier W (2008) PAMAM dendrimer-based multifunctional fluorescent conjugates for improved fluorescent labelling of macromolecules. Chemistry – A European Journal 14(27), 8116-8130.

  • Wängler C, Moldenhauer G, Eisenhut M, Haberkorn U, Mier W (2008) Antibody-Dendrimer Conjugates: The Number, Not the Size of the Dendrimers, Determines the Immunoreactivity. Bioconjugate Chemistry 19(4), 813-820.

  • Wängler C, Eisenhut M, Haberkorn U, Mier, W (2008) Improved syntheses and applicability of different DOTA building blocks for multiply derivatized scaffolds. Bioorganic and Medicinal Chemistry 16, 2606-2616.


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