Short CV/Education and training


  • 1977
    High school degree, latin-greek-philosophy, Como, Italy

  • 1981
    Bachelor of Science in Pharmacology & Toxicology, Biochemistry and Vegetal Physiology, University of Lausanne.

  • 1986
    Doctor of Philosophy in Toxicology, mention "summa cum laude" University of Lausanne, Switzerland.

  • 1998

Professional experience:

  • 1987
    Postdoctoral fellow Institute of Pharmacology & Toxicology, University of Lausanne (Prof. J. Diezi)

  • 1988
    Postdoctoral fellow, Occupational Health Sciences Institute, University of Lausanne, Switzerland (Prof. H.Savolainen & Prof.M. Guillemin)

  • 1988 – 1991
    Postdoctoral fellow at the Swiss Institute on Experimental Cancer Research, Epalinges, Switzerland (Dr. P. Cerutti)

  • 1991 – 1993
    Postdoctoral fellow at the National Cancer Institute, Laboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, USA (Dr. C.C. Harris)

  • 1993 – 1999
    Lecturer, Institute of Pharmacology & Toxicology, University of Lausanne (Prof. J. Diezi)

  • 1999 – 2006
    Substitute Assistant professor, Institute of Pharmacology & Toxicology, University of Lausanne

  • 2006
    Invited scientist DKFZ, Heidelberg

  • since 2007
    group leader, Laboratory of Molecular Oncology, Clinic of Oncology, Lungen- und Thoraxonkologie Zentrum of Zurich University Hospital

Selected publications

  • THURNEYSEN C, OPITZ I, KURTZ S, WEDER W, STAHEL RA, FELLEY-BOSCO E. Functional inactivation of NF2/merlin in human mesothelioma. Lung Cancer. 2009 64(2):140-7

  • SIDI R, PASELLO G, OPITZ I, SOLTERMANN A, TUTIC M, REHRAUER H, WEDER W, STAHEL RA, FELLEY-BOSCO E Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: An exploratory analysis. European Journal of Cancer 47 (2011), pp. 326-332

  • *FREI C, OPITZ I, SOLTERMANN A, FISCHER B, MOURA U, REHRAUER H, WEDER W, STAHEL R, FELLEY-BOSCO E. Pleural mesothelioma side populations have a precursor phenotype. Carcinogenesis, 2011 32(9):1324-32

  • Y SHI, U MOURA, I OPITZ, A SOLTERMANN, H REHRAUER, S THIES, W WEDER, RA. STAHEL AND E FELLEY-BOSCO Role of hedgehog signaling in malignant pleural mesothelioma, Clinical Cancer Research, 2012 18:4646-56

  • A. RENGANATHAN, J KRESOJA-RAKIC, N ECHEVERRY, G ZILTENER, B VRUGT, I OPITZ, R A. STAHEL & E FELLEY-BOSCO GAS5 long non-coding RNA in malignant pleural mesothelioma. Molecular cancer, 05/2014; 13(1):119.

  • STAHEL, R.A., FELLEY-BOSCO, E., OPITZ, I., WEDER, W. Malignant pleural mesothelioma. Future Medicine. Future Oncol. ;5:391-402, 2009

  • FELLEY-BOSCO E AND R STAHEL Hippo/YAP pathway for targeted therapy. Transl Lung Cancer Res 2014;3(2):75-83

  • FELLEY-BOSCO E, OPITZ I, Mesothelioma. In: Lung Cancer Therapy Annual 7. Edited by Rolf A. Stahel. Informa Healthcare USA, Inc., New York 2012

Complete list of publications

Selected projects

  • From asbestos-exposure to cancer: a systemic approach to detect loss of homeostatic control in the mesothelial environment

  • Preclinical Malignant Pleural Mesothelioma Models To Accelerate Clinical Research On Targeted Therapies

Membership in scientific bodies/juries

  • Swiss Society of Pharmacology and Toxicology , IASLC

Media coverage



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