Short CV/Education and training

  • 1975 – 1981
    Studied biology at the University of Hamburg, Germany

  • 1981
    Diplom degree in biology

  • 1985 – 1987
    Postdoctoral fellow at the Max Planck Institute of Cell Biology, Ladenburg, Germany

  • 1988 – 1992
    Postdoctoral fellow at the Institute of Plant Sciences, Federal Institute of Technology (ETH) in Zurich, Switzerland

  • 1992 – 2003
    Research associate at the Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland

  • 2000
    Habilitation (postdoctoral qualification) in botany, University of Basel, Switzerland

  • Since 2004
    Senior group leader at the Gregor Mendel Institute of Molecular Plant Biology (GMI), Vienna, Austria

  • 2006
    Habilitation (postdoctoral qualification) in genetics, University of Vienna, Austria

  • 2007 – 2009
    Scientific director ad interim at the Gregor Mendel-Institute of Molecular Plant Biology (GMI)

Selected publications

  • Pecinka, A., Fang, W., Rehmsmeier, M., Levy, A.A., Mittelsten Scheid, O. (2011) Polyploidization increases meiotic recombination frequency in Arabidopsis. BMC Biology, Biology 9:24

  • Pecinka, P., Dinh, H.Q., Baubec, T., Rosa, M, Lettner, N., Mittelsten Scheid, O. (2010) Epigenetic regulation of repetitive elements is attenuated by prolonged heat stress in Arabidopsis. Plant Cell 22: 3118-3129

  • Baubec, T., Dinh, H.Q., Pecinka, A., Rakic, B., Rozhon, W., Wohlrab, B., von Haeseler, A., Mittelsten Scheid, O. (2010) Cooperation of multiple chromatin modifications can generate unanticipated stability of epigenetic states in Arabidopsis. Plant Cell 22: 34-47

  • Pecinka, A., Rosa, M., Schikora, A., Berlinger, M., Hirt, H., Luschnig, C., Mittelsten Scheid, O. (2009) Transgenerational stress memory is not a general response in Arabidopsis. PLoS One 4: e5202

  • Hetzl, J., Foerster, A.M., Raidl, G., Mittelsten Scheid, O. (2007) CyMate: a new tool for methylation analysis of plant genomic DNA after bisulphate sequencing. Plant J 51:526-536

  • Probst, A.V., Fagard, M., Proux, F., Mourrain, P., Boutet, S., Earley, K., Lawrence, R.J., Pikaard, C.S., Murfett, J., Furner, I., Vaucheret, H., Mittelsten Scheid, O. (2004) Arabidopsis histone deacetylase HDA6 is required for maintenance of transcriptional gene silencing and determines nuclear organization of rDNA repeats. Plant Cell. 16:1021-1034

  • Mittelsten Scheid, O., Afsar K. and Paszkowski, J. (2003) Formation of stable epialleles and their paramutation-like interaction in tetraploid Arabidopsis thaliana. Nature Genetics 34: 450-454

  • Saze, H., Mittelsten Scheid, O. and Paszkowski, J. (2003) Maintenance of CpG methylation is essential for epigenetic inheritance during plant gametogenesis. Nature Genetics, 34: 65-69

  • Probst, A.V., Fransz, P.F., Paszkowski, J. and Mittelsten Scheid, O. (2002) Two means of transcriptional reactivation within heterochromatin. Plant J., 33(4): 743-749

  • Mittelsten Scheid, O., Probst, A.V., Afsar K. and Paszkowski, J. (2002) Two regulatory levels of transcriptional gene silencing in Arabidopsis. Proc. Natl. Acad. Sci. USA 99: 13659-13662

  • Amedeo, P., Habu, Y., Afsar, K., Mittelsten Scheid, O. and Paszkowski, J. (2000) Disruption of the plant gene MOM releases transcriptional silencing of methylated genes. Nature 405: 203-206

  • Steimer, A., Amedeo, P., Afsar, K., Mittelsten Scheid, O. and Paszkowski, J. (2000) Endogenous targets of transcriptional gene silencing in Arabidopsis. Plant Cell 12: 1165-1178

  • Mittelsten Scheid, O., Afsar, K. and Paszkowski, J. (1998) Release of epigenetic silencing by trans-acting mutations in Arabidopsis. Proc. Natl. Acad. Sci. USA 95: 532-637

  • Diéguez, M.J., Vaucheret, H., Paszkowski, J. and Mittelsten Scheid, O. (1998) Cytosine methylation at CG and CNG sites is not a prerequisite for the initiation of transcriptional gene silencing in plants but it is required for its maintenance. Mol. Gen. Genet. 259: 207-215

  • Mittelsten Scheid, O., Jakovleva, L., Afsar, K., Maluszynska Y. and Paszkowski, J. (1996) A change of ploidy can modify epigenetic silencing. Proc. Natl. Acad. Sci. USA 93: 7114-7119

  • Mittelsten Scheid, O., Paszkowski, J. and Potrykus, I. (1991) Reversible inactivation of a transgene in Arabidopsis thaliana. Mol. Gen. Genet. 228: 104-112



Complete list of publications

Selected projects

  • EEFG/Austrian Science Fund (FWF) Grant "Epicol", 2010 – 2013

  • Austrian Science Fund (FWF), 2006 – 2011

  • European Union (EU) Network of Excellence (NoE Epigenome), 2006 – 2009

  • GENome Research in AUstria Project (GEN-AU), 2006 – 2009

  • European Union (EU) "Biotechnology V", 2001 – 2003

  • European Union (EU) "Biotechnology IV", 1997 – 1999

  • European Union (EU) "Human capital and mobility", 1994 – 1996

  • Swiss National Foundation (SNF) (associated investigator), 1992 – 1994

Membership in scientific bodies/juries

  • Co-editor of Plant Cell, since 2010

  • Co-editor of Scientific Reports, since 2011

  • Reporter for the Board of the Austrian Science Fund (FWF), since 2008

  • Gene technology commission of the Austrian Federal Ministry of Health, since 2009

  • AERES evaluation of the GReD at Clermont-Ferrant, France, 2011

  • Advisory Board Member of the NSF Consortium "Functional Genomics of Plant Polyploids", USA, 2006 – 2009

  • Evaluation Biosciences Research Network Saxony-Anhalt, Germany, 2008

  • Reviewer for several grant agencies and journals

  • Communicating science, for example, participating in the Lange Nacht der Forschung ("long night of research" outreach programme), GEN-AU Summer School, Mentoring Programme Sprungbrett für Mädchen ("springboard for girls"), advisor to Dialog – Gentechnik ("dialogue – genetic engineering")

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