PD Dr. Silvia Capellino

• Since 2017: Member of the medical faculty of the University Duisburg-Essen

• Since 2016
  Leader of the Junior Research Group „Neuroimmunology“ at the Leibniz Research Centre for Working Environment and Human Factors, at the Technical University Dortmund (IfADo) and Marie Skłodowska-Curie scholarship holder
  
  

• 2015 – 2016
  PostDoc (University of Giessen and Kerckhoff Clinic, Bad Nauheim, Germany)
  
  

• 2014
  Maternity leave
  
  

• 2012 – 2013
  PostDoc (The Johns Hopkins University, School of Medicine, Baltimore MD, USA)
  
  

• 2012
  Habilitation (University of Regensburg, Germany)
  
  

• 2007 – 2012
  PostDoc (University of Regensburg, Germany)
  
  

• 2007
  Ph.D. on Clinical and Experimental Immunology (University of Genoa, Italy and University of Regensburg, Germany)
  
  

• 2003
  Diploma in Biology (University of Genoa, Italy)
  
  

• Novaira HJ, Graceli JB, Capellino S, Schoeffield A, Hoffman GE, Wolfe A, Wondisford F, Radovick S. Development and characterization of novel rat anti-mERβ sera. Endocrinology. 2016;157(7):2844-52.

• Capellino S, Cosentino M, Luini A, Bombelli R, Lowin T, Cutolo M, Marino F, Straub RH. Increased expression of dopamine receptors in synovial fibroblasts of rheumatoid arthritis patients – inhibitory effects of dopamine on IL-8 and IL-6. Arthritis Rheumatol. 2014;66(10):2685-93

• Jenei-Lanzl Z, Capellino S, Kees F, Fleck M, Lowin T, Straub RH. Anti-inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis. Ann Rheum Dis. 2015;74(2):444-51

• Capellino S, Gelder M, Weber K, Härle P, Straub RH. First appearance and location of catecholaminergic cells during experimental arthritis, and elimination by chemical sympathectomy. Arthritis Rheum 2012 ;64(4):1110

• Capellino S, Cosentino M, Wolff C, Schmidt M, Grifka J, Straub RH. Catecholamine-producing cells in the synovial tissue during arthritis: modulation of sympathetic neurotransmitters as new therapeutic target. Ann Rheum Dis. 2010;69(10):1853-60.

• Capellino S, Montagna P, Villaggio B, Soldano S, Straub RH, Cutolo M. Hydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia. Clin Exp Rheumatol. 2008;26(5):903-9

• Straub RH, Grum F, Strauch U, Capellino S, Bataille F, Bleich A, Falk W, Schölmerich J, Obermeier F. Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation. Gut. 2008;57(7):911-21.

• Capellino S, Riepl B, Rauch L, Angele P, Cutolo M, Straub RH. Quantitative determination of steroid hormone receptor positive cells in the synovium of patients with rheumatoid arthritis and osteoarthritis: is there a link to inflammation? Ann Rheum Dis. 2007;66(1):53-8.

• Cutolo M, Capellino S, Montagna P, Sulli A, Seriolo B, Villaggio B. Anti-inflammatory effects of leflunomide in combination with methotrexate on co-culture of T lymphocytes and synovial macrophages from rheumatoid arthritis patients. Ann Rheum Dis. 2006;65(6):728-35.

• Cutolo M, Maestroni GJ, Otsa K, Aakre O, Villaggio B, Capellino S, Montagna P, Fazzuoli L, Veldi T, Peets T, Hertens E, Sulli A. Circadian melatonin and cortisol levels in rheumatoid arthritis patients in winter time: a north and south Europe comparison. Ann Rheum Dis. 2005;64(2):212-6.

• MARIE CURIE individual Fellowship (EU Horizon2020), Title: DeBoRA (Dopamine and bone metabolism in rheumatoid arthritis)

• Start-up price funded by the DGRh, Title: The dopamine pathway: a potential therapeutic target for local treatment of rheumatoid arthritis

• DFG funded grant (CA933/1-1) within the research unit FOR696 (Molecular Analyses and Interactions at Articular Interfaces), Title: Rolle von Tyrosin-Hydroxylase (TH) – positiven Zellen im Rahmen des Entzündungsgeschehens bei Arthritis

• Speaker of the GEBIN (German Endocrine Brain Immune Network)

• Member of the DGRh (Deutsche Gesellschaft für Rheumatologie) and DHV (Deutscher Hochschulverband)

Other activities and achievements/family

• Mother of two children (4 and 7 years old).

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