Short CV/Education and training

  • 1999
    PhD in Biochemistry at the University of Barcelona

  • 2002
    Postdoctoral fellow in Plant Molecular Biology at the Rockefeller University

  • 2004
    Postdoctoral Associate in Structural Biology at WMC of Cornell University and MSKCC

  • 2008
    Ramon y Cajal Researcher at the University of Barcelona. Topic: Role of SUMO in plants

    To date: CSIC assistant professor. Topic: regulation of SUMO conjugation in vivo. Biotechnological applications.

Selected publications

  • Castaño-Miquel, L., Seguí, J., Manrique, S., Teixeira, I., Carretero-Paulet, L., Atencio, F., and Lois, L. M. (2013) Diversification of SUMO-Activating Enzyme in Arabidopsis: Implications in SUMO Conjugation, Molecular plant 6, 1646-1660.

  • Castaño-Miquel, L., Seguí, J., and Lois, L. M. (2011) Distinctive properties of Arabidopsis SUMO paralogues support the in vivo predominant role of AtSUMO1/2 isoforms, Biochemical Journal 436, 581-590.

  • Lois, L. M. (2010) Diversity of the SUMOylation machinery in plants, Biochemical Society transactions 38, 60-64.

  • Chosed, R., Mukherjee, S., Lois, L. M., and Orth, K. (2006) Evolution of a signalling system that incorporates both redundancy and diversity: Arabidopsis SUMOylation, Biochemical Journal 398, 521-529.

  • Lois, L. M., and Lima, C. D. (2005) Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1, EMBO J 24, 439-451.

  • Lois, L. M., Lima, C. D., and Chua, N. H. (2003) Small ubiquitin-like modifier modulates abscisic acid signaling in Arabidopsis, Plant Cell 15, 1347-1359.

  • Lois, L. M., Rodriguez-Concepcion, M., Gallego, F., Campos, N., and Boronat, A. (2000) Carotenoid biosynthesis during tomato fruit development: regulatory role of 1-deoxy-D-xylulose 5-phosphate synthase, Plant J. 22, 503-513.

  • Lois, L. M., Campos, N., Putra, S. R., Danielsen, K., Rohmer, M., and Boronat, A. (1998) Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis, Proc. Natl. Acad. Sci. U. S. A. 95, 2105-2110.

Selected projects

  • BM1307. 2013-2017. European network to integrate research on intracellular proteolysis pathways in health and disease (PROTEOSTASIS), COST, European Union.

  • ERC-2007StG-205927. 2008-2014. Study of the role of protein posttranslational modification by SUMO (Small Ubiquitin-like Modifier) in abscisic acid signaling and stress responses in plants. European Research Council.

  • BIO2008-01495. 2009-2012. Role of SUMO during seed development. Ministerio de Ciencia e Innovación. Spain.


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