Short CV/Education and training

  • 1983
    Abitur (A-levels), Steglitz Gymnasium (grammar school) for the humanities, Berlin, Germany

  • 1984 – 1988
    Studied Chemistry at TU Berlin

  • 1988
    Diplom thesis at the Max Planck Institute for Molecular Genetics, Berlin

  • 1989 – 1992
    Doctoral thesis at the Institute for Genetic Biological Research, Berlin

  • 1992 – 1993
    Postdoc in developmental biology at Stanford University, USA

  • 1999
    Habilitation (postdoctoral qualification), Ulm University, Germany

Selected publications

  • Hölzle, A. et al.: Maturation of the 5S rRNA 5' end is catalysed in vitro by the endonuclease tRNase Z in the archaeon Haloferax volcanii. In: RNA 14, 2008. pp. 928-937.

  • Späth, B. et al.: Analysis of the functional modules of the tRNA 3' endonuclease (tRNase Z). In: J Biol Chem 280, 2005. pp. 35440-35447.

  • Dubrovsky, E. B. et al.: Drosophila RNase Z processes mitochondrial and nuclear pre-tRNA 3' ends in vivo. In: Nucleic Acids Res 32, 2004. pp. 255-262.

  • Pellegrini, O. et al.: Endonucleolytic processing of CCA-less tRNA precursors by RNase Z in Bacillus subtilis. In: EMBO J 22, 2003. pp. 4534-4543.

  • Kruszka, K. et al.: Plant dicistronic tRNA-snoRNA genes: a new mode of expression of the small nucleolar RNAs processed by RNase Z. In: EMBO J 22, 2003. pp. 621-632.

  • Schiffer, S., Rösch, S., Marchfelder, A.: Assigning a function to a conserved group of proteins: The tRNA 3' processing enzymes. In: EMBO J 21, 2002. pp. 2769-2777.

  • Kunzmann, A., Brennicke, A., Marchfelder, A.: 5' end maturation and RNA editing have to precede tRNA 3' processing in plant mitochondria. In: Proc Natl Acad Sci, USA 95, 1998. pp. 108-113.

Selected projects

  • RNA metabolism in archaea

Membership in scientific bodies/juries

  • Advisory board of the Society of Biochemistry and Molecular Biology (GMB) study group RNA Biochemistry


You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here


  1. Read what our members say about AcademiaNet.

No more excuses!

  1. Please download the brochure "No more excuses" and read more about female experts in Europe, and about AcademiaNet.

Similar profiles

  1. Dr. Jessica Abbott

    Biological and related sciences Evolutionary biology, Evolutionary genetics

  2. Dr. Chantal Abergel

    Biological and related sciences , Physical sciencesEnvironmental virology, Molecular and structural biology, biochemistry

  3. Prof. Dr. Heike Allgayer

    Biological and related sciences , Health

  4. Dr. Sonja-Verena Albers

    Biological and related sciences Molecular biology, molecular microbiology, biochemistry, membrane protein biochemistry