Short CV/Education and training

  • 1991
    PhD in genetic epidemiology from the Erasmus University Rotterdam

  • Since 2001
    Full professor of Genetic Epidemiology at the Department of Epidemiology of the Erasmus University Medical Center

  •  
    Prof van Duijn's work focuses on omics research in neurodegenerative disorders. She has identified genes involved in various neurodegenerative disorders including Alzheimer's disease, Parkinson disease, CreutzfeldtJakob disease and open angle glaucoma.

  • Since 2014
    Member of the Royal Academy of Sciences

Selected publications

  • Van Duijn CM, Knijff P de, Cruts M, Wehnert A, Havekes LM, Hofman A, Broeckhoven C van. Apolipoprotein E E4 allele in a population-based study of early-onset Alzheimer's disease. Nature Genetics 1994;7:74-78.

  • Van Duijn CM, Delasnerie Laupretre N, Masullo C, Zerr I, de Silva R, Wientjens DPWM, Brandel J-P, Weber T, Bonavita V, Zeidler M, Alperovitch A, Poser S, Granieri E, Hofman A, Will RG. For the EU Collaborative Study Group for CJD. Case-control study of risk factors of Creutzfeldt Jakob disease in Europe during 1993 95. Lancet 1998;351:1081-1085.

  • Njajou OT, Vaessen N, Joosse M, Berghuis B, Dongen JWF van, Breuning MH, Snijders PJLM, Rutten WPF, Sandkuijl LA, Oostra BA, Van Duijn CM, Heutink P. A mutation in SLC11A3 gene is associated with autosomal dominant hemochromatosis. Nature Genetics 2001;28:214-215.

  • Bonifati V, Rizzu P, van Baren J, Schaap O, Breedveld GJ, Krieger E, Dekker MCJ, Squitieri F, Ibanez P, Joosse M, Dongen JW van, Vanacore N, Swieten JC van, Brice A, Meco G, Van Duijn CM, Oostra BA, Heutink P. Mutations in the DJ-1 gene associated with autosomal rececessive early-onset parkinsonism. Science 2003;299:256-259.

  • Despriet DD, Klaver CC, Witteman JC, Bergen AA, Kardys I, Boekhoorn SS, Vingerling JR, Hofman A, Oostra BA, Uitterlinden AG, Stijnen T, Duijn CM van, Jong PT de. Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration. JAMA 2006;296:301-9.

  • Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Döring A, Wichmann HE, Smit JH, McCarthy MI, Van Duijn CM, Peltonen L (shared last authorship).; for the ENGAGE Consortium. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nature Genetics 2009; 41:47-55.

  • Levy D, Ehret GB, Rice K, Verwoert GC, Harris TB, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Launer LJ, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Guo X, Arking DE, Mitchell GF, Mattace-Raso FUS, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJH, Bis J, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JCM, Boerwinkle E, Wang TJ, Larson MG, Chakravarti A, Psaty BM, Van Duijn CM. Significant Association of Common Genetic Variation at Three Loci with Blood Pressure: A genomewide association study from four population-based cohort studies and in silico replication and meta-analysis. Nat Genet 2009;41:677-87.

  • Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, Duijn CM van, Breteler MM(shared last authorship).; CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010;303:1832-40.

  • Teslovich TT, Musunuru K, Smith AV, Edmondson C, .Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis G Boehnke M,Kathiresan S (shared last authorship). Biological, Clinical, and Population Relevance of 95 Loci Mapped for Serum Lipid Concentrations. Nature 2010; 466:707-713.

  • Solouki AM, Verhoeven VJ, van Duijn CM, Verkerk AJ, Ikram MK, Hysi PG, Despriet DD, van Koolwijk LM, Ho L, Ramdas WD, Czudowska M, Kuijpers RW, Amin N, Struchalin M, Aulchenko YS, van Rij G, Riemslag FC, Young TL, Mackey DA, Spector TD, Gorgels TG, Willemse-Assink JJ, Isaacs A, Kramer R, Swagemakers SM, Bergen AA, van Oosterhout AA, Oostra BA, Rivadeneira F, Uitterlinden AG, Hofman A, de Jong PT, Hammond CJ, Vingerling JR, Klaver CC. A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nat Genet 2010; 42:897-901.


Selected projects

  • Principle investigator in three large-scale population- and family-based studies: the Erasmus Rucphen Family (ERF) study, the Rotterdam study and Generation R.

  • Leader in several international genome wide association consortia including CHARGE (Cohorts for Heart & Aging Research in Genome Epidemiology, ENGAGE (European Network for Genetic and Genomic Epidemiology), and EAGLE (Early Genetics and Life course Epidemiology).

Membership in scientific bodies/juries

Selected scientific committees:

  • American Society for Human Genetics (ASHG)

  • International Society for Genetic Epidemiology (IGES)

  • European Society for Human Genetics (ESHG)

  • Molecular Epidemiology Group

Additional qualifications

  • Program Direct of the Genetic Epdemiology Master Program of the Netherlands Institute for Health Sciences


Soft Skills/Other activities and achievements

Additional interests

  • Genetic Risk prediction

  • Big data

  • eScience


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