Short CV/Education and training

  • 1965 – 1972
    Studied medicine at the Bulgarian Academy of Medicine; completed Medical Degree (M.D.)

  • 1972
    Gold Medal of the Bulgarian Academy of Medicine

  • 1973 – 1988
    Research associate in the laboratory for regenerative research, in the neurochemistry section, at the Bulgarian Academy of Sciences, Sofia

  • 1974 – 1976
    Fellowship from the Foundation for European Neurosciences

  • 1975
    Specialisation at the "Brain Research Institute" at the University of Tokyo, Japan

  • 1980 – 1981
    Fellowship from the Alexander von Humboldt Foundation; additional training and research in neurochemistry at the Max Planck Institute of Experimental Medicine in Göttingen, Germany

  • 1982 – 1985
    Additional training in the Institute of Molecular Biology at the Bulgarian Academy of Sciences in Sofia, Bulgaria

  • 1988 – 1989
    Fellowship from the Alexander von Humboldt Foundation; additional training in the area of molecular and developmental biology and research as a research associate at the Max Planck Institute for Biophysical Chemistry in Göttingen

  • 1989 – 1991
    Adjunct professor at the Institute of Molecular Biology in Sofia, Bulgaria

  • 1991 – 2002
    Research associate at the Max Planck Institute for Biophysical Chemistry, in the molecular cell biology section, Göttingen

  • 2002 – 2008
    Head of the research group "Molecular developmental neurobiology" in the molecular cell biology section at the Max Planck Institute for Biophysical Chemistry, Göttingen

  • Since 2008
    Max Planck Society (MPG) Fellow; head of an independent research group (MPG W2 professor, Minerva Programme) at the Max Planck Institute for Biophysical Chemistry, Göttingen

  • Since 2010
    Professor by special appointment, developmental neurobiology, University of Göttingen, Germany

Selected publications

  • Tuoc, T.C. et al.: Layer specific defects and behavioral abnormalities in the cortex specific Pax6 knock out mouse. In: Journal of Neuroscience 29, 2009. pp. 8335-8349.

  • Tuoc, T.C., Stoykova, A.: Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin proteosome system. In: Genes & Development 22, 2008. pp. 1972-1986.

  • Pinon, M.C. et al.: Altered molecular regionalization and normal thalamocortical connections in cortex-specific Pax6 knock-out mice. In: Journal of Neuroscience 28, 2008. pp. 8724-8734.

  • Fimia, G.M. et al.: AMBRA1 regulates autophagy and development of the nervous system. In: Nature 447, 2007. pp. 1121-1125.

  • Berger, J. et al.: Conditional activation of Pax6 in the developing cortex of transgenic mice causes progenitor apoptosis. In: Development 134, 2007. pp. 1311-1322.

  • Remedios, R. et al.: A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. In: Nature Neuroscience 10, 2007. pp. 1141-1150.

  • Mallamaci, A., Stoykova, A.: Gene network controlling early cerebral cortex arealisation. In: European Journal of Neuroscience 23, 2006. pp. 847-856.

  • Muzio, L. et al.: Conversion of cerebral cortex into basal ganglia in Emx2-/-Pax6 sey/sey double-mutant mice. In: Nature Neuroscience 5, 2002. pp. 737-745.

  • Stoykova, A. et al.: Pax6 modulates the dorso-ventral patterning of the mammalian telencephalon. In: Journal of Neuroscience 20, 2000. pp. 8042-8050.

  • Götz, M. et al.: Pax6 controls radial glial differentiation in the cerebral cortex. In: Neuron 21, 1998. pp. 1031-1044.

  • Stoykova, A., Gruss, P.: Roles of Pax-genes in developing and adult brain as suggested by expression patterns. In: Journal of Neuroscience 14, 1994. pp. 1395-1312.


Selected projects

  • Focus of research: molecular and cellular mechanisms that underlie the development of the vertebrate brain, with a particular focus on corticogenesis in mammals, e.g.: mechanisms for pattern formation during the development of the central nervous system,

  • Genetic mechanisms for the specification of layers and areas within the developing mammalian cortex,

  • Pax6-dependent molecular mechanisms of neurogenesis in the developing neocortex,

  • Control of neurogenesis by the transcription factor Scratch2,

  • Function of BAF170, a sub-unit of the chromatin-remodelling complex SWI/SNF in the formation of neuronal diversity in the cortex,

  • Mechanisms of neurogenesis after ischaemia in the adult mammalian brain

Membership in scientific bodies/juries

  • Member of the American Society for Neuroscience

Reviewer for funding applications

  • WELLCOME TRUST, UK

  • Biotechnology and Biological Sciences Research Council (BBSRC), UK

  • Italian Ministry for Education, University and Research (MIUR)

Reviewer for the journals

  • Journal of Neuroscience

  • Neuroscience

  • Genes and Development

  • Journal of Comparative Neurology

  • Development

  • Cerebral Cortex

  • Journal of European Neuroscience

  • Member of the faculty of the International Max Planck Research School (IMPRS) for Neurosciences/University of Göttingen

  • Member of the faculty of the Graduate School for Neurosciences and Molecular Biological Sciences (GGNB), Göttingen

  • Member of the faculty of the EU Marie Curie Training Programme NEUREST (Neuroscience Early Stage Research Training)

Additional qualifications

  • Recognition of the Habilitation (second postdoctoral qualification) and received the venia legendi (authorisation to teach) for the subject developmental biology in Faculty of Medicine at the University of Göttingen, Germany, 2002


Soft Skills/Other activities and achievements

Soft Skills

  • Married, one daughter


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