Short CV/Education and training

Education

  • 1980 – 1986
    Study of Medicine, University of Heidelberg, Germany

  • 1982 – 1986
    Doctoral thesis, University of Heidelberg, Germany

  • 1990
    Habilitation in Experimental Virology, University of Heidelberg, Germany

Career

  • 1986 – 1991
    Postdoc, Institute of Medical Virology, University of Heidelberg, Germany

  • 1991 – 1993
    Postdoc, Institute of Hygiene, University of Heidelberg, Germany

  • 1993 – 1995
    Childcare leave

  • since 1995
    Head of Clinical Research, Department of Pediatrics, University of Technology Dresden, Germany

Other Academic Positions

  • since 2003
    Apl. Professor University of Technology Dresden, Germany

  • since 2003
    Member of the Promotionskommission – Faculty of Medicine – University of Technology Dresden, Germany

Selected publications

  • Luksch H, Romanowski MJ, Chara O, Tüngler V, Caffarena ER, Heymann M, Lohse P, Aksentijevich, Remmers EF, Flecks S, Quoos N, Gramatté J, Petzold C, Hofmann SR, Winkler S, Pessler F, Kallinich T, Ganser G, Nimtz-Talaska A, Baumann U, Runde V, Grimbacher B, Birmelin J, Gahr M, Roesler J, Rösen-Wolff A (2012). Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1beta (IL-1beta). Hum Mut 2012 Jul 25. doi: 10.1002/humu.22169.

  • Winkler S, Heyman MC, Franke M, Martin A, Roesler J, Rösen-Wolff A (2012). A Protective Role for Inflammasome Activation Following Injury. SHOCK, Vol. 37 (6):659.

  • Groessl, M, Luksch H, Rösen-Wolff A, Shevchenko A, Gentzel M (2012): Profiling of the human monocyte secretome by quantitative label-free mass spectrometry identifies stimulus ?specific cytokines and inflammation-related proteins. J Proteomics 2012 Jul 26. doi: 10.1002/pmic.201200108.

  • Hofmann SR, Morbach H, Schwarz T, Rösen-Wolff A, Girschick HJ, Hedrich CM (2012). Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression. Clin Immunol 2012 Oct;145(1):69-76. doi: 10.1016/j.clim.2012.07.012. Epub 2012 Aug

  • Hofmann SR, Rösen-Wolff A, Hahn G, Hedrich CM (2012). Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO), International Journal of Rheumatology, vol. 2012, Article ID 310206, 7 pages, 2012. doi:10.1155/2012/310206.

  • Seckinger A, Meißner T, Moreaux J, Witte D, Hillengas J, Hose K, Reme T, Rösen-Wolff A, Jauch A, Schnettler R, Ewerbeck V, Goldschmidt H, Klein B, Hose D (2012). Clinical and prognostic role of Annexin A2 in multiple Myeoloma . Blood 2012 Jun 15.

  • Landsberg C, Deutsch A, Rösen-Wolff A, Gelinsky M, Voigt A (2011). Chemotaxis of mesenchymal stem cells within 3D biomimetic scaffolds-a modeling approach. J Biomechanics 44 (2): 359-364.


Selected projects

  • Klinische Forschergruppe 249 "Defekte des angeborenen Immunsystems bei autoinflammatorischen und autoimmunologischen Erkrankungen" – TP 1 "Inflammasom-assoziierte Defekte der zytoplasmatischen DAMP-Erkennung – Einfluss von Mutationen im CASP1 -Gen auf Transkription, Zytokinfreisetzungsmuster und Pyroptose", Deutsche Forschungsgemeinschaft, 2010-2013

  • Verbundprojekt: Deutsches Netzwerk für Primäre Immundefekte (PID-NET), TPA4 "Autoinflammatorische Erkrankungen", Bundesministerium für Bildung und Forschung, 2009-2015

  • SFB/TRR79 "Werkstoffe für die Geweberegeneration im systemisch erkrankten Knochen" – TP M4 "Etablierung des neuen Ansatzes "in situ Tissue Engineeríng" für die Knochendefektheilung" –

    Deutsche Forschungsgemeinschaft 2010-2015

Membership in scientific bodies/juries

  • Arbeitsgemeinschaft Pädiatrische Immunologie (API)

Soft Skills/Other activities and achievements

Soft Skills

  • certified conflict manager


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