Short CV/Education and training

  • 1964
    Abitur (A-levels) and certificate in agriculture at the Volkshochschule (adult education centre), Leipzig, Germany

  • 1964 – 1969
    Studied biology at the University of Greifswald, Germany

  • 1969
    Diplom degree in biology with specialisation in genetics

Selected publications

  • Wobus, A.M. (2010): The Janus face of pluripotent stem cells--connection between pluripotency and tumourigenicity. In: BioEssays 32/11, S. 993-1002.

  • Rolletschek et al. (2010): Characterization of mouse embryonic stem cell differentiation into the pancreatic lineage in vitro by transcriptional profiling, quantitative RT-PCR and immunocytochemistry. In: Int. J. Dev. Biol. 54, S. 41-54.

  • Nikolova et al. (2007): WNT-conditioned media differentially affect the proliferation and differentiation of cord blood-derived CD133+ cells in vitro. In: Differentiation 75(2), S. 100-111.

  • Wiese et al. (2006): Signals from embryonic fibroblasts induce adult intestinal epithelial cells to form nestin-positive cells with proliferation and multilineage differentiation capacity in vitro. In: Stem Cells 24(9), S. 2085-2097.

  • Schröder et al. (2006): Differentiation of mouse embryonic stem cells to insulin-producing cells. In: Nature Protocols 1(2), S. 495-507.

  • Kania et al. (2005): Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors. In: Stem Cells 23(6), S. 791-804.

  • Blyszcuk et al. (2003): Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. In: Proc. Natl. Acad. Sci. 100, S. 998-1003.

  • Wobus, A.M. et al. (2002): Methods Molecular Biology Series 185, Humana Press Inc., Totowa, NJ, USA. S. 127-168.

  • Rohwedel et al. (1998): Loss of beta1 integrin function results in a retardation of myogenic, but an acceleration of neuronal, differentiation of embryonic stem cells in vitro. In: Dev. Biol. 201, S. 167-184.

  • Fässler et al. (1996): Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin. In: J. Cell Sci. 109, S. 2989-2999.

  • Maltsev, V.A., J. Rohwedel, J. Hescheler, A.M. Wobus (1993): Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types. In: Mech. Dev. 44, S. 41-50.

  • Wobus, A.M., H. Holzhausen, Jäkel, J. Schöneich (1984): Characterization of a pluripotent stem cell line derived from a mouse embryo. In: Exp. Cell Res. 152, S. 212-219.


Selected projects

  • Numerous past projects funded by the German Research Foundation (DFG), the German Federal Ministry of Education and Research (BMBF), and the European Union (EU)

  • Currently: BMBF project within the competence network Diabetes Mellitus

  • AKROBAT: Advance Knowledge for Restoration of Beta Cells and Diabetes Therapy

Membership in scientific bodies/juries

  • Member of the National Academy of Sciences Leopoldina

  • Member of the Berlin-Brandenburg Academy of Sciences and Humanities (BBAW)

  • Member of the Central Ethics Committee for Stem Cell Research (ZES), deputy chair

  • Member of the Novartis Ethics Advisory Board (NEAB), Novartis International, Basel, Switzerland

  • Member of the BBAW research group Gene Technology Report

  • Member of the scientific advisory board of the Research Centre Saxony-Anhalt, Germany

  • Associate editor, Cells Tissues Organs, Karger, Basel, Switzerland

  • Member of the editorial boards of the scientific journals Stem Cells; Int. J. Dev. Biol.; J. of Stem Cells; J. Tissue Eng. & Reg. Med.

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