Short CV/Education and training

  • 1971
    Pharmaceutical state examination at Marburg University, Germany

  • 1973 – 1975
    PhD student in the Department of Neurochemistry, Max Planck Institute of Experimental Medicine, Göttingen, Germany

  • 1975
    Doctor of Natural Science (Dr rer. nat.) in biology from the University of Göttingen

  • 1977
    Visiting researcher, with a Minerva fellowship, in the Department of Neurobiology at the Weizmann Institute, Rehovot, Israel

  • 1978 – 1979
    Postdoctoral Fellow in the Department of Neuroscience, Harvard Medical School, Boston, MA, USA

  • 1979 – 1980
    Postdoctoral Fellow in the Department of Neurobiology, Stanford University School of Medicine, Stanford, CA, USA

  • 1983 – 1988
    Research associate in the Biology section, University of Bremen, Germany

  • 1985 – 1986
    Visiting researcher in the Department of Molecular Neurogenetics, Eunice Kennedy Shriver Centre, Waltham, MA, and in the Department of Genetics, Harvard Medical School, Boston, MA, USA

  • 1988
    Habilitation (postdoctoral qualification) in biology at the University of Bremen, field of specialisation: molecular neurobiology

  • 1988 – 1990
    Research director and quality assurance manager, International Bio Research (IBR), Walsrode and Hannover, Germany

  • 1990 – 1991
    Freelance staff member at International Bio Research (scientific consulting)

  • 1992 – 1993
    Senior lecturer (C2) in the Biology/Chemistry section, University of Bremen

  • Since 1993
    University professor (C3) in the Biology section, University of Oldenburg, Germany; director of the Molecular Neurobiology/Neurochemistry research group

  • 1998 – 1999
    Visiting professor at the Centre for Neurodegenerative Disease Research (CNDR), University of Pennsylvania School of Medicine, Philadelphia, USA

  • 2003 – 2004
    Visiting professor at the Centre for Neurodegenerative Disease Research (CNDR), University of Pennsylvania School of Medicine, Philadelphia USA

Selected publications

  • Goldbaum, O., Richter-Landsberg, C.: Proteolytic stress causes heat shock protein induction, tau-ubiquitination and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture. In: J. Neuroscience 24, 2004. pp. 5748-5757.

  • Goldbaum, O. et al.: Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes. In: Glia 53, 2006. pp. 891-901.

  • Richter-Landsberg, C.: The cytoskeleton in oligodendrocytes: Microtubule dynamics in health and disease. In: J. Mol. Neurosci. 35, 2008. pp. 55-63.

  • Goldbaum, O. et al.: The expression of tubulin polymerization promoting protein TPPP/p25? is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress. In: Glia 56, 2008. pp. 1736-1746.

  • Riedel, M. et al.: Alpha-Synuclein promotes the recruitment of tau to protein inclusions in oligodendroglial cells: effects of oxidative and proteolytic stress. In: J. Mol. Neurosci. 39, 2009. pp. 226-234.

  • Riedel, M. et al.: 17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy. In: PlosOne 5(1), 2010. pp. 1-9. e8753. doi: 13.1371/journal.pone.0008753.

  • Jänen, S., Chaachouay, H., Richter-Landsberg, C. : Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes. Glia 58: 1766-1744 (2010)

  • Seiberlich V et al. : Inhibition of protein deubiquitination by PR-619 activates the autophagic pathway in OLN-t40 oligodendroglial cells. Cell Biochemistry and Biophysics 67: 149-160 (2013)

  • Richter-Landsberg, C., Leyk, J. : Inclusion body formation, macroautophagy, and the role of HDA6 in neurodegeneration. Acta Neuropathologica 126: 793-807 (2013)

  • Noack, M., Leyk, J., Richter-Landsberg, C. : HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes. Glia 62: 535-547 (2014)

  • Seiberlich, V., et al. : Downregulation of the microtubule associated protein Tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes. Glia 63: 1031-1635. doi: 10.1002/glia.22832. Epub 2015 Apr 4. (2015)

  • Richter-Landsberg, C.: Protein Aggregate Formation In Oligodendrocytes: Tau And The Cytoskeleton At The Intersection Of Neuroprotection And Neurodegeneration. Biological Chemistry 396: 185-194 oi: 10.1111/jnc.13256. Epub 2015 Aug 12. (2016)

  • Leyk, J., et al.: HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness. Cell Death and Disease 8 , e3028; doi: 10.1038/cddis. 2017.415 (2017)



Complete list of publications

Selected projects

  • The role of stress proteins and their importance for nerve cells and glia

  • Regulation of cell death and the survival of brain cells

  • Molecular mechanisms underlying the formation of protein deposits in neurodegenerative diseases (Alzheimer Disease, Multiple System Atrophy, Parkinson Disease)

  • Oxidative stress in oligodendrocytes and in demyelinating diseases

  • The functional role of the cytoskeleton in oligodendrocytes, the myelin-forming cells of the central nervous system

  • Microtubules and associated proteins (Tau proteins)

Membership in scientific bodies/juries

  • Member of the scientific advisory board for the Society for Progressive Supranuclear Palsy (Cure PSP), USA

  • Member of the editorial board for the Journal of Molecular Neuroscience

  • Member and former contact person for the Society for Biochemistry and Molecular Biology (GBM) at the University of Oldenburg, Germany

  • Member of the Society for Neuroscience

  • Member of the International Society of Neurochemistry

  • Member of the European Society for Neurochemistry

Additional qualifications

  • Scientific consulting in cell and molecular biology, for the cosmetic and pharmaceutical industries


Soft Skills/Other activities and achievements

Additional interests

  • Consulting in cell and molecular biology, biomedicine


Soft Skills

  • Music: violin


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