Short CV/Education and training

  • 1976
    Abitur (A-levels)

  • 1976 – 1981
    Studied biology and chemistry at the University of Regensburg, Germany

  • 1981
    State examination in Regensburg

  • 1982
    Research assistant in the working group on physical biochemistry under Prof. E. Holler, University of Regensburg

  • 1983 – 1986
    Dissertation in natural science at the Max Planck Institute of Biochemistry, Department of Connective Tissue Research, under Prof. K. Kühn

  • 1986
    Doctorate from the Faculty of Natural Science III, Biology and Preclinical Medicine, University of Regensburg

  • 1986 – 1991
    Research associate at the Connective Tissue Research Laboratory, University Dermatological Clinic, Munich, Germany, under Prof. Th. Krieg, MD

  • 1991
    Research associate at the Dermatology and Venereology Clinic, University of Cologne, Germany; director: Prof. Th. Krieg, MD

  • 1985 – 1990
    Studied medicine at Ludwig Maximilian University (LMU) Munich

  • 1986
    Preclinical examination

  • 1987
    1st state examination, 1989 2nd state examination, 1990 3rd state examination

  • 1988
    Visiting researcher at M.D. Anderson Institute and Cancer Centre, Department of Genetics, Houston, Texas, under Prof. B. de Crombrugghe, Chairman

  • 1988 – 1990
    Medical dissertation at the Connective Tissue Research Laboratory, University Dermatological Clinic, Munich, under Prof. Th. Krieg, MD

  • 1991 – 1993
    Visiting researcher with funding from the AIDS fellowship programme of the German Cancer Research Centre (DKFZ Heidelberg) at Stanford University, Department of Dermatology, Stanford, California, USA, under Prof. E. Bauer, Chairman

  • 1993
    Doctorate from the Faculty of Medicine, LMU Munich

  • 1993 – 1996
    Further training to become a doctor of dermatology and venereology at the Hospital and Outpatient Clinic for Dermatology and Venereology, University of Cologne, director: Prof. Th. Krieg, MD

  • 1996
    Recognised as doctor of dermatology and venereology by the North Rhine Medical Chamber

  • 1997
    Habilitation (postdoctoral qualification) and granting of the venia legendi (authorisation to teach) in the field of dermatology and venereology

  • 1997 – 2003
    C2 senior consultant at the University Dermatological Clinic of Cologne

  • Since 2003
    C3 professor of dermatology and venereology at the Hospital and Outpatient Clinic for Dermatology, University Hospital of Cologne

  • 2001 – 2005
    Member of the executive committee, German Dermatological Research Consortium (ADF), treasurer

  • Since 2003
    Member of the research advisory board, Cologne Fortune

  • 2003 – 2009
    Member of the executive committee, European Society of Dermatological Research (ESDR)

  • 2006
    Additional specialist training in Medicinal Tumour Therapy

  • Since 2006
    Authorisation to provide specialist training in Medicinal Tumour Therapy

  • Since 2006
    Examiner in Medicinal Tumour Therapy for the North Rhine Medical Chamber

  • 2007 – 2009
    Member of the executive committee, German Dermatological Oncology Consortium (ADO)

  • Since 2008
    Member of the German Research Foundation (DFG) review board, Cancer Research Section

  • Since 2010
    Director of the Skin Cancer Centre, University Hospital of Cologne (certified as of 6th October 2010 in accordance with DIN EN ISO and OnkoZert)

  • Since 2010
    Dean of research, University Hospital of Cologne

  • Since 2010
    Chairperson of the endowments and research funding advisory board, the Cologne Fortune research advisory board and the Clinical Studies Research Pool advisory board, Faculty of Medicine, University of Cologne

Selected publications

  • Löffek S, Zigrino P, Angel P, Anwald B, Krieg T, Mauch C. High invasive melanoma cells induce MMP-1 synthesis and activation in fibroblasts by interleukin-1alpha and basic fibroblast growth factor-mediated mechanisms. J Invest Dermatol.124:638-643 (2005)

  • Gallagher PG, Bao Y, Prorock A, Zigrino P, Nischt R, Politi V, Mauch C, Deagulev B, Fox JW. Gene expression profiling reveals cross-talk between melanoma and fibroblasts: Implications for host-tumor interactions in metastasis. Cancer Res. 65: 4134-4146 (2005)

  • Chometon G, Rubinstein E, Mauch C, Aumailley M. Dissociation of the complex between CD151 and laminin-binding integrins induces migration of epithelial cells, Exp Cell Res 312(7): 983-95 (2006)

  • Zigrino P, Steiger J, Fox JW, Löffek S, Schild A, Nischt R, Mauch C. Role of ADAM-9 disintegrin-cysteine rich domains in human keratinocyte migration. J Biol Chem. 282(42):30785-93 (2007)

  • Zigrino P, Kuhn I, Bäuerle T, Zamek J, Fox JW, Neumann S, Licht A, Schorpp-Kistner M, Angel P, Mauch C. Stromal expression of MMP-13 is required for melanoma invasion and metastasis. J Invest Dermatol 129(11):2686-93 (2009)

  • Wieland U, Mauch C, Kreuter A, Krieg T, Pfister H. Merkel cell polyomavirus DNA in persons without merkel cell carcinoma. Emerg Infect Dis. 2009 Sep;15(9):1496-8

  • Seeger JM, Schmidt P, Brinkmann K, Hombach AA, Coutelle O, Zigrino P, Wagner-Stippich D, Mauch C, Abken H, Krönke M and Kashkar H. The proteasome inhibitor Bortezomib sensitizes melanoma cells towards adoptive CTL attack Cancer Res 1;70(5):1825-34 (2010)

    Mauch C, Zamek J, Abety AN, Grimberg G, Fox JW, Zigrino P: Role of ADAM-9 during wound repair. J Invest Dermatol 130(8): 2120-2130 (2010)


Membership in scientific bodies/juries

  • Molecular diagnostics (German Dermatological Society)

  • S3 guidelines for radiotherapy

  • CIO Centre for Integrated Oncology, Cologne & Bonn, Germany

  • German Dermatological Research Consortium (ADF)

  • European Society for Dermatological Research (ESDR)

  • German Society for Connective Tissue Research (DGBF)

  • European Tissue Repair Society (ETRS)

  • International Society for Matrix Biology (ISMB)

  • German Cancer Society

  • German Dermatological Society (DDG)

  • German Dermatological Oncology Consortium (ADO)

  • ADO commission on clinical studies

Additional qualifications

Reviewer for the following journals

  • Archives of Dermatological Research

  • Biochemical Pharmacology

  • Cell and Tissue Research

  • European Journal of Dermatology

  • Experimental Dermatology

  • Haut- and Geschlechtskrankheiten (Skin and Venereal Diseases)

  • International Journal of Cancer

  • Journal of Biological Chemistry

  • Journal of Cell Biology

  • Journal of Investigative Dermatology (JID)

  • Laboratory Animal Science

  • Matrix Biology

  • Phlebologie (Phlebology)


Soft Skills/Other activities and achievements

Soft Skills

  • Lectures on the prevention of skin cancer, for example at schools and in the context of the Children's University of Cologne


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