Short CV/Education and training

  • 1971 – 1976
    Studied biology, University of Münster, Germany

  • 1981
    Doctorate in zoology

  • 1982 – 1986
    Postdoc with Peter Hausen at the Max Planck Institute in Tübingen, Germany

  • 1986 – 1992
    Head of a research group in the Institute of Molecular Biology and Biochemistry at the Freie Universität (FU) Berlin, Germany. Research on the function of cadherins and extracellular matrix proteins in the early embryogenesis of Xenopus

  • 1992 – 2001
    Professor of biochemistry at Ulm University, Germany

  • Since 2001
    Professor in the Zoological Institute, Department of Cell and Developmental Biology at the Karlsruhe Institute of Technology (KIT), Germany

Selected publications

  • Etard, C. et al.: Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1. In: Mech. Dev. 122, 2005. pp. 545-556.

  • Vogelmann, R. et al.: TGFβ-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN. In: J Cell Sci. 118, 2005. pp. 4901-4912.

  • Ghogomu, S. et al.: Hic-5 a novel regulator of Lef/Tcf activity modulates the crosstalk between Wnt-signalling and steroid receptor activity. In: J. Biol. Chem. 281, 2006. pp. 1755-1764.

  • Köbernick, K. et al.: Xenopus Teashirt1 regulates posterior identity in brain and cranial neural crest. In: Dev Biol. 298, 2006. pp. 312-326.

  • Ruan, G., Wedlich, D., Köhler, A.: Xenopus Cadherin-6 regulates growth and epithelial development of the retina. In: Mech. Dev. 123 (12), 2006. pp. 881-892.

  • Schambony, A., Wedlich, D.: Wnt-5a/Ror2 regulate expression of XPAPC through an alternative non-canonical signaling pathway. In: Dev. Cell 12, 2007. pp. 779-792.

  • Kalinina, S. et al.: Isothiocyanate-functionalized RGD peptides for tailoring cell-adhesive surface patterns. In: Biomaterials 29(20), 2008. pp. 3004-3013.

  • Kashef, J. et al.: Cadherin-11 regulates protrusive activity in Xenpous cranial neural crest cells upstream of Trio and the small GTPases. In: Genes & Development 23, 2009. pp. 1393-1398.

  • Montero-Pancera, S. et al.: Design of Chemically Activated Polymer Microwells by One-Step UV-Lithography for Stem Cell Adhesion. In: Langmuir 26(3), 2009. pp. 2050-2056.

  • Engin, S. et al.: Benzylguanine Thiol Self-Assembled Monolayers for the Immobilization of SNAP-tag Proteins on Microcontact-Printed Surface Structures. In: Langmuir 26(9), 2010. pp. 6097-6101.


Selected projects

  • Biofunctionalisation of nano- and microstructured surfaces (funded by the German Research Foundation (DFG), CFN centre for excellence)

  • The Wnt-signalling network in gastrulation movement (DFG, Wnt Research Unit Heidelberg)

  • Regulation of neural crest migration (DFG individual grant)

Membership in scientific bodies/juries

  • Member of the advisory board of the German Society for Cell Biology (DGZ), since 2008

  • Co-organiser of the 12th International Xenopus Conference, 2008

  • Vice dean of the Faculty of Chemistry and Biological Sciences at the University of Karlsruhe, Germany, 2007 – 2010

  • Member of the board of trustees of the GFZ German Research Centre for Geosciences in Potsdam, since 2006

  • Member of the senate committee for the Collaborative Research Centres of the German Research Foundation (DFG), since 2005

  • Organiser of the 2nd DFG Symposium on "Cell Migration in Development and Disease", 2004

  • Vice dean, University of Karlsruhe (TH), 2002 – 2005

  • Member of the research group "Molecular Biology" of the German Research Foundation (DFG), 2001 – 2004

  • Member of the DFG reviewer panel on the life sciences, 2001 – 2004

  • Vice dean of the Faculty of Biosciences and Geosciences at the University of Karlsruhe, 2001 – 2002

  • Co-organiser of the 14th scientific congress of the German Society for Developmental Biology (GfE), 2001

  • Co-organiser of the 1st DFG Symposium on "Cell Migration in Development and Disease", 2001

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