Short CV/Education and training

  • Since 2009
    Professor of neurology (W3) and director of the Department of Neurology at the University Medical Center of the Johannes Gutenberg University Mainz, Germany

  • 2006
    Professor (W3) and head of the Cécilie Vogt Clinic for Neurology, Charité Berlin; starting in 2007, in collaboration with the HELIOS-Klinikum Berlin-Buch. Concurrent appointment as the coordinator of the clinic and head of an independent research group for molecular neurology at the Max Delbrück Center for Molecular Medicine (MDC), Berlin-Buch; member of the executive board of the MDC

  • 2005
    Offer of a chair in neurology at Queen Mary University in London, UK

  • 2002
    Professor of neuroimmunology (C3) at Charité Berlin and head of the Institute for Neuroimmunology

  • 2001
    Offer of a priority professorship in neurology (C3) at the University of Göttingen, Germany

  • 1998
    Senior consultant in neurology at Charité Berlin

  • 1998
    Specialist and Habilitation (postdoctoral qualification) in the field of neurology at the University of Tübingen, Germany

  • 1995
    Research associate in neurology under Prof. Dr. med. J. Dichgans at the Tübingen University Hospital; within the framework of a research project: Visiting Scientist under Prof. H. McFarland at the National Institutes of Health, Neuroimmunology Branch, Bethesda, MD, USA

  • 1993
    Fellowship from the German Research Foundation (DFG) and the Hertie Foundation in the neuroimmunology department under Prof. Dr. med. H. Wekerle and R. Hohlfeld at the Max Planck Institute of Psychiatry, Martinsried, Germany

  • 1990
    Doctorate in neuromorphology from Goethe University Frankfurt, Germany

  • 1989
    Research associate in neurology at the university hospital at Goethe University Frankfurt

  • 1982
    Studied at Goethe University Frankfurt, in North America (Duke University, North Carolina; Sick Childrens' Hospital, Toronto) and in London, England

Selected publications

  • Siffrin, V. et al.: In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis. In: Immunity 33, 2010. pp. 424-436.

  • Schulze-Topphoff, U. et al.: Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system. In: Nature Medicine 15, 2009. pp. 788-793.

  • Aktas, O. et al.: Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. In: Neuron 46, 2005. pp. 421-432.

Membership in scientific bodies/juries

  • Speaker for the Collaborative Research Centre/Transregio (SFB-TR) 128 "Initiating/Effector versus Regulatory Mechanisms in Multiple Sclerosis -

    Progress towards Tackling the Disease", since 2012

  • Member of the International Advisory Board of the Institute of Brain and Spinal Cord Diseases of the University Hospital Pitié-Salpetrière, Paris

  • Member of the ECTRIMS (European Congress of Treatment in Multiple Sclerosis) Council

  • Member of the Gutenberg Research Unit at Mainz University

  • Organization of the International Conference for Neuroimmunology 2014 in Mainz (rmn2 – Rhine-Main Neuroscience Network)

  • Co-coordinator of the German Federal Ministry of Education and Research (BMBF) Competence Network "Multiple Sclerosis"

  • Deputy chairperson of the medical advisory board of the German Multiple Sclerosis Society (DMSG)

  • Board member of the German Multiple Sclerosis Society, Rhineland-Palatinate state chapter

  • Chairperson of the scientific advisory committee to BayImmuNet, named to the position by the Bavarian State Ministry of Sciences

  • Speaker for the Transfer Project SFB: Transregio TRR 43 "The brain as a target of inflammatory processes", 2008-2009 (departure)

  • Member of the Board of Directors of the Excellence Cluster NeuroCure - towards a better outcome of neurological diseases, 2007-2009 (departure)

  • Speaker for the DFG Research Training Group GRK 1258/1 "The influence of inflammation on the functioning of the nervous system", 2006-2009 (departure)

  • Board member of the Collaborative Research Centre SFB 507 "The importance of non-neuronal cells in neurological disorders", 2004-2007

  • Board member of the Hertie Institute for MS research at the University Medical Center Göttingen, 2002-2008

Soft Skills/Other activities and achievements

Additional interests

  • Multiple sclerosis


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