Short CV/Education and training

  • 1980 – 1985
    Studied human biology at Marburg University, Germany

  • 1985 – 1988
    Doctor of Natural Science (Dr rer. nat.) in the group of K. Rajewsky, Institute of Genetics, University of Cologne, Germany

  • 1988 – 1990
    Postdoc, Institute of Genetics, University of Cologne

  • 1990 – 1993
    Postdoc in the group of D. Hanahan, University of California, San Francisco, USA

  • 1993 – 1998
    Group leader at the Institute of Genetics, University of Cologne

  • 1998
    Appointed University Professor (C3) at the Technical University of Munich, Germany

  • 1998 – 2004
    Director of a Volkswagen Foundation junior research group at the Institute of Medical Microbiology, Immunology and Hygiene and the Department of Internal Medicine II, Technical University of Munich

  • 2004
    Appointed University Professor (C3) of Molecular Immunology at Heinrich Heine University of Düsseldorf, Germany

  • Since 2005
    Member of the advisory board for the German Immunological Society (DGfI)

  • 2005 – 2012
    Director of the Molecular Immunology section at the IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf

  • Since 2012
    Professor (W3) of immunology and environment in the Life and Medical Sciences (LIMES) Institute at the University of Bonn, Germany

Selected publications

  • Clausen, B.E. et al.: Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transg. Res. 8: 265-277, 1999.

  • Takeda, K. et al.: Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10: 39-49, 1999.

  • Alferink, J. et al.: Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J. Exp. Med. 197: 585-599, 2003.

  • Cramer, T. et al.: HIF-1 is essential for myeloid cell-mediated inflammation. Cell 112: 645-657, 2003.

  • Buch, T. et al.: MHC class II expression through a hitherto unknown pathway supports T helper cell dependent immune responses: implications for MHC class II deficiency. Blood 107, 1434-1444, 2006.

  • Semmling, V. et al.: Alternative cross-priming through CCL17/CCR4-mediated CTL attraction towards NKT cell-licensed dendritic cells. Nat. Immunol. 11: 313-20, 2010.

  • Stutte, S. et al.: Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells. Proc. Natl. Acad. Sci. USA 107: 8736-41, 2010.

  • Winter, M. et al.: Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells. Nanotoxicology, Sep 16. [Epub ahead of print], 2010


Selected projects

  • Collaborative Research Centre (SFB) 704,TP A1: Regulation of immune responses via chemokine- and cytokine-mediated interactions of T cells and dendritic cells. (2006-2013)

  • FOR729,TP 5: Metabolic regulation of inflammatory reactions: HIF-1alpha and IDO as anti-infectious effector-mechanisms of professional phagocytes (2007-2013)

  • GK1427, TP 9: Effects of nanoparticles on inflammation and genotoxicity in the intestines. PI: I. Förster and R. Schins (2006-2012)

  • Jürgen Manchot Foundation, the Manchot graduate programme "Molecules of Infection", TP 9: TLR-induced natural immunity and defence against infection in aryl-hydrocarbon receptor repressor (AhRR)-deficient mice. (2010-2013)

Membership in scientific bodies/juries

  • Member of the advisory board, German Immunological Society (DGfI)

  • Member of the DGfI training committee

Additional qualifications

  • Immunology expert for the German Immunological Society (DGfI), since 2002


Soft Skills/Other activities and achievements

Soft Skills

  • 1 son, born 2003


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