Short CV/Education and training

  • 1990
    Abitur (A-levels)

  • 1990 – 1995
    Studied biochemistry, Leibniz University Hannover, Medical University Hannover (MHH), University of Veterinary Medicine Hannover

  • 1993
    Research associate, section for structural biology, Max Planck Institute of Biochemistry, Martinsried/Munich, Germany

  • 1994
    Research associate, Department for Molecular and Cell Biology, University of California, Berkeley, CA, USA

  • 1994
    Research associate, Institute of Experimental Immunology, University of Zurich and University Hospital Zurich, Switzerland

  • 1994
    Research associate, Department of Biochemistry, University of Zurich, Switzerland

  • 1995
    Diplom degree in biochemistry, Leibniz University Hannover and Medical University Hannover (MHH)

  • 1995
    Diplom thesis, Department of Biochemistry, University of Zurich, Switzerland

  • 1996 – 2000
    Dissertation, Department of Biochemistry, University of Zurich, and Department for Molecular and Cell Biology, University of California, Berkeley, CA, USA

  • 1997
    Visiting researcher, Department of Biochemistry, University of Montreal, Montreal (Quebec), Canada

  • 1998 – 2000
    Visiting researcher, Department for Molecular and Cell Biology, University of California, Berkeley, USA

  • 2000
    Dissertation in biochemistry (Dr sc. nat.) at the University of Zurich, Switzerland

  • 2000
    Researcher (postdoc), Department of Molecular and Cell Biology, University of California, Berkeley, USA

  • 2000 – 2002
    Researcher (postdoc), Department of Biology II (Biochemistry), University of Freiburg, Germany

  • 2001 – 2002
    Parental leave

  • 2002 – 2003
    European Molecular Biology (EMBO) researcher (postdoc), Department of Biology III - molecular biology and genetics, University of Freiburg

  • 2003 – 2008
    Head of an Emmy Noether junior research group (German Research Foundation (DFG) Excellence Programme) Department of Biology III - molecular biology and genetics, University of Freiburg

  • 2003 – 2004
    Parental leave

  • Since 2007
    BIOSS research group leader, Excellence Cluster Biological Signalling Studies, University of Freiburg

  • Since 2008
    Junior Fellow FRIAS – LIFENET, Freiburg Institute for Advanced Studies (FRIAS), School of Life Sciences (LIFENET), University of Freiburg

  • Since 2010
    Professor of molecular biotechnology, Institute of Biochemistry and Biology, University of Potsdam, Germany

Selected publications

  • Zhang, F. et al.: Photocontrol of coiled-coil proteins in living cells. In: Angew. Chem. Int. Ed. 49(23), 2010. pp. 3943-3946.

  • Mason, J.M., Hagemann, U.B., Arndt, K.M.: Role of Hydrophobic and Electrostatic Interactions in Coiled Coil Stability and Specificity. In: Biochemistry 48(43), 2009. pp. 10380-10388.

  • Mason, J.M., Müller, K.M., Arndt, K.M.: Peptides Tailored to Interfere with Protein Interaction and Function. In: Chemistry Today 27(2), 2009. pp. 47-50.

  • Jouaux, E.M. et al.: Improving the Interaction of Myc-Interfering Peptides with Myc Using Molecular Dynamics Simulations. In: J. Pept. Sci. 15(1), 2009. pp. 5-15.

  • Mason, J.M., Müller, K.M., Arndt, K.M.: iPEP: peptides desigend and selected for interfering with protein interaction and function. In: Biochem Soc Trans. 36(6), 2009. pp. 1442-1447.

  • Hagemann, U.B. et al.: Selectional and mutational scope of peptides sequestering the c-Fos coiled coil domain. In: J. Mol. Biol. 381(1), 2008. pp. 73-88.

  • Jouaux, E.M. et al.: Targeting the c-Myc coiled coil with interfering peptides to inhibit DNA binding. In: J. Pept. Sci. 14(9), 2008. pp. 1022-1031.

  • Mason, J.M., Hagemann, U.B., Arndt, K.M.: Improved stability of the Jun-Fos Activator Protein-1 coiled coil motif: A stopped-flow circular dichroism kinetic analysis. In: J. Biol. Chem. 282(32), 2007. pp. 23015-23024.

  • Mason, J.M., Müller, K.M., Arndt, K.M.: Positive Aspects of Negative Design: Simultaneous Selection of Specificity and Interaction Stability. In: Biochemistry 46(16), 2007. pp. 4804-4814.

  • Mason, J.M. et al.: Semirational design of Jun-Fos coiled coils with increased affinity: Universal implications for leucine zipper prediction and design. In: Proc. Natl. Acad. Sci. USA 103(24), 2006. pp. 8989-8994.

  • Müller, K.M. et al.: Nucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolution. In: Nucleic Acids Research 33(13), 2005. e117.

  • Mason, J.M., Arndt, K.M.: Coiled coil domains: stability, specificity, and biological implications. In: ChemBioChem 5(2), 2004. pp. 170-176.



Complete list of publications

Selected projects

  • Photo-controlled transcription factors for probing how mice form memories; collaborative research project funded by the Human Frontier Science Program (HFSP)

  • The role of transcription factors in tumour cell invasion: AP-1 and Myc inhibitors for interfering with tumour growth and metastasis; Sub-project C1 in the Collaborative Research Centre SFB 850: Control of cell motility during morphogenesis, tumour invasion and metastasis

  • Analysis and programming of transmembrane signalling by nanoscale patterns: Modified DNA origami as input for B- and T-cells; Project in the Excellence Cluster BIOSS (Centre for Biological Signalling Studies)

Additional qualifications

  • Junior Fellow, Freiburg Institute for Advanced Studies, Freiburg, Germany, 2008 – 2011

  • Emmy Noether group leader (rather than Habilitation (postdoctoral qualification)), 2003 – 2008


Soft Skills/Other activities and achievements

Soft Skills

  • Baden-Württemberg Ministerial Certificate for the acquisition of competence in university teaching

  • Participation in project management and personnel management seminars


Other activities and achievements/family

  • Family

    4 children

    Parental leave: 02/2001 – 07/2002 and 07/2003 – 12/2004


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