Short CV/Education and training

  • 1991 – 1996
    Diploma studies of biotechnology Technical University of Braunschweig, Germany

  • 1994 – 1995
    Short thesis with Dr. Gursharan S. Chhatwal: Interaction of Streptococcus pneumoniae with host proteins. Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig, Germany

  • 1996
    Diploma studies with Dr. Michael Nerenberg: Perturbations in signal transduction pathways and cell cycle regulation in HTLV-I transformed cells. The Scripps Research Institute (TSRI), San Diego, USA

  • 1997 – 2000
    PhD studies in cell biology (summa cum laude), Friedrich Miescher Institute, Basel, Switzerland

  • 2000 – 2003
    Postdoctoral studies with Prof. Jane E. Visvader and Prof. Geoffrey J. Lindeman: The role of XIAP in the mammary gland. Interaction of 14-3-3 proteins with the prolactin receptor. Identification of the lipid transfer protein StarD10 and its role in breast epithelial cell transformation. The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Australia

  • 2004
    Independent Research Scientist: Regulation of the StarD10 lipid transfer protein by phosphorylation. University of Ulm, Department of Pharmacology and Toxicology, Germany

  • 2004 – 2005
    Independent Research Scientist: Identification of DLC1 protein binding partners. Regulation of the StarD10 lipid transfer protein by phosphorylation. University of Stuttgart, Institute of Cell Biology and Immunology, Germany

  • 2005 – 2011
    Group Leader: Physiological functions and regulation of the DLC tumor suppressor family. Lipid transfer proteins in organelle function, signaling and disease. University of Stuttgart, Institute of Cell Biology and Immunology, Germany

  • Since 2011
    Heisenberg Professor of Molecular Tumor Cell Biology (W3; permanent position): Oncogenes – novel regulatory mechanisms for ErbB receptors. Tumor suppressors: DLC proteins – Three proteins, three functions? University of Stuttgart, Institute of Cell Biology and Immunology, Germany

Selected publications

  • Holeiter, G., Bischoff, A., Braun, A. C., Huck, B., Erlmann, P., Schmid, S., Herr, R., Brummer, T., and Olayioye, M. A. (2012). The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity. Oncogenesis 1, e13; doi:10.1038/oncsis.2012.13

  • Heering, J., Weis, N., Holeiter, M., Neugart, F., Staebler, A., Fehm, T. N., Bischoff, A., Schiller, J., Duss, S., Schmid, S., Korte, T., Herrmann, A., and Olayioye, M. A. (2012). Loss of the ceramide transfer protein augments EGF receptor signaling in breast cancer. Cancer Res., 72, 2855-2866.

  • Scholz, R., Regner, J., Holeiter, G., Theil, A., Erlmann, P., Jähne, R., Schmid, S., Hausser, A., and Olayioye, M. A. (2009). DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling. J. Cell Sci. 122, 92-102.

  • Holeiter, G., Heering, J., Erlmann, P., Schmid, S., Jähne, R., and Olayioye, M. A. (2008). Deleted in Liver Cancer 1 controls cell migration through a Dia1-dependent signaling pathway. Cancer Res. 68, 8743-8751.

  • Fugmann, T., Hausser, A., Schöffler, P., Schmid, S., Pfizenmaier, K. and Olayioye, M. A. (2007). Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer protein. J. Cell. Biol. 178, 15-22.

    This paper is recommended by the Faculty of 1000 and rated "of special interest" by D'Angelo et al. 2008. Lipid-transfer proteins in biosynthetic pathways. Curr. Opin. Cell Biol. 20: 360-370.

  • Olayioye, M. A., Vehring, S., Müller, P., Hermann, A., Schiller, J., Thiele, C., Lindeman, G. J., Visvader J. E. and Pomorski, T. (2005). StarD10, a START domain protein overexpressed in breast cancer, functions as a lipid transfer protein. J. Biol. Chem. 280, 27436-27442.

  • Olayioye, M. A., Hoffmann, P., Pomorski, T., Armes, J., Simpson, R. J., Kemp, B. E., Lindeman, G. J. and Visvader, J. E. (2004). The phosphoprotein StarD10 is overexpressed in breast cancer and cooperates with ErbB receptors in cellular transformation. Cancer Res. 64, 3538-3544.

  • Olayioye, M. A., Neve, R. M., Lane, H. A. and Hynes N. E. (2000). The ErbB signaling network: roles for receptor homo- and heterodimers in development and cancer. EMBO J. 19, 3159-3167.


Membership in scientific bodies/juries

  • Editorial Board Member of Cancer Research, 2013 – 2015

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