Short CV/Education and training

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Selected publications

  • Tews D, Fromme T, Keuper M, Hofmann SM, Debatin KM, Klingenspor M, Wabitsch M, Fischer-Posovszky P: Teneurin-2 (TENM29 deficiency induces UCP-1 expression in differentiating human fat cells. Mol Cell Endocrinol. 2017 Mar 5;443:106-113.

  • Roos J, Enlund E, Funcke JB, Tews D, Holzmann K, Debatin KM, Wabitsch M, Fischer-Posovszky P: miR-146a-mediated suppression of the inflammatory response in human adipocytes. Sci Rep. 2016 Dec 6;6:38339.

  • Zoller V, Funcke JB, Keuper M, Abd El Hay M, Debatin KM, Wabitsch M, Fischer-Posovszky P: TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors. Cell Death Dis. 2016 Oct 13;7(10):e2412.

  • Wabitsch M, Funcke JB, von Schnurbein J, Denzer F, Lahr G, Mazen I, El-Gammal M, Denzer C, Moss A, Debatin KM, Gierschik P, Mistry V, Keogh JM, Farooqi IS, Moepps B, Fischer-Posovszky P: Severe early-onset obesity due to bioinactive leptin caused by a p.N103K mutation in the leptin gene. J Clin Endocrinol Metab. 2015 Sep;100(9):3227-30.

  • Fischer-Posovszky P, Funcke JB, Wabitsch M: Biologically inactive leptin and early-onset extreme obesity. N Engl J Med. 2015 Mar 26;372(13):1266-7.

  • Wabitsch M, Funcke JB, Lennerz B, Kuhnle-Kral U, Lahr G, Debatin KM, Vatter P, Gierschik P, Moepps B, Fischer-Posovszky P: Biologically inactive leptin and early-onset extreme obesity. N Engl J Med. 2015 Jan 1;372(1):48-54

  • Funcke JB, Zoller V, Abd El Hay M, Debatin KM, Wabitsch M, Fischer-Posovszky P: TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation. FASEB J. 2015 Jul;29(7):3065-75.

  • Fischer-Posovszky P, Wang Q, Asterholm IW, Rutkowski JM, Scherer PE: Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2-macrophages. Endocrinology. 2011 Aug;152(8):3074-81.

  • Keuper M, Blüher M, Schön M, Möller P, Dzyakanchuk A, Amrein K, Debatin KM, Wabitsch M, Fischer-Posovszky P: Obesity-associated macrophage infiltration in human adipose tissue is linked to apoptosis of fat cells. Mol Cell Endocrinol. 2011 Jun 6;339(1-2):105-13.



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