Short CV/Education and training

  • 1989
    Abitur (A-levels), Erich Weinert extended grammar school (EOS), Flöha, Germany

  • 1990 – 1991
    Studied mathematics at Chemnitz University of Technology, Germany

  • 1991 – 1997
    Studied medicine at Freie Universität (FU) Berlin, Germany

  • 1996 – 1997
    Studied medicine in the USA: Mount Sinai Medical School, NY; University of California at San Diego; Mayo Medical School, Rochester, NY

  • 1998 – 1999
    Physician, German Heart Institute (DHZB), Berlin

  • 1999
    Full physician's licence

  • 1999
    Doctorate from the Physiological Institute, Freie Universität (FU) Berlin

  • 1999 – 2000
    Postdoc in molecular biology, Max Planck Institute for Molecular Genetics, Berlin

  • 2001 – 2010
    Head of the Cardiovascular Genetics research group, Max Planck Institute for Molecular Genetics, Berlin

  • 2005
    Attained level of achievement equivalent to Habilitation (postdoctoral qualification)

  • 2009
    Habilitation (postdoctoral qualification), Charité

  • 2010
    W3 Heisenberg Professor of cardiovascular genetics

  • 2011
    University professor of cardiovascular genetics, Experimental and Clinical Research Centre (Charité & MDC); Director, Medical Clinic with focus on molecular und clinical Cardiology, Campus Berlin-Buch, Charité

  • since 2011
    Koopted Professor at the department of Biology, Chemistry und Pharmacy, Freie Universität Berlin

  • since 2014
    Guest scientist at the Max-Planck Institute for molecular Genetics, Berlin

  • 2014
    Special Volunteer at National Heart Lung Institute, Bethesda, USA

Selected publications

  • Rickert-Sperling S, Kelly R, Driscoll DJ, editors. Congenital Heart Diseases: The Broken Heart: Clinical Features, Human Genetics and Molecular Pathways. 1st ed. Springer-Verlag Wien. 2015

  • Grunert M, Dorn C, Schueler M, Dunkel I, Schlesinger J, Mebus S, Alexi-Meskishvili V, Perrot A, Wassilew K, Timmermann B, Hetzer R, Berger F & Sperling RS (2014) Rare and private variations in neural crest, apoptosis and sacromere genes define the polygenic background of isolated Tetralogy of Fallot. Hum Mol Genet 23:3115-3128

  • Schlesinger J, Schueler M, Grunert M, Fischer JJ, Zhang Q, Krueger T, Lange M, Tönjes M, Dunkel I & Sperling SR (2012) The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet 7: e1001313

  • Sperling SR. Systems biology approaches to heart development and congenital heart disease. Cardiovasc Res. 2011 Jul 15;91(2):269–78.

  • Lange M, Kaynak B, Forster U, Tonjes M, Fischer J, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S & Sperling S (2008) Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev 22: 2370–2384

  • Vogel JH, Heydebreck von A, Purmann A, Sperling S. Chromosomal clustering of a human transcriptome reveals regulatory background. BMC Bioinformatics. 2005;6:230. 5.

  • Fischer J, Toedling J, Krueger T, Schueler M, Huber W, Sperling S. Combinatorial effects of four histone modifications in transcription and differentiation. Genomics. 2008;91(1):41–51.

  • Sperling S, Grimm CH, Dunkel I, Mebus S, Sperling H-P, Ebner A, et al. Identification and functional analysis of CITED2 mutations in patients with congenital heart defects. Hum Mutat. 2005 Dec;26(6):575–82.

  • Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest ARR, Zavolan M, Davis MJ, ... Sperling S, ... et al (2005) The transcriptional landscape of the mammalian genome. Science 309: 1559–1563

  • Kaynak B, Heydebreck von A, Mebus S, Seelow D, Hennig S, Vogel J, Sperling H-P, Pregla R, Alexi-Meskishvili V, Hetzer R, Lange PE, Vingron M, Lehrach H & Sperling S (2003) Genome-wide array analysis of normal and malformed human hearts. Circulation 107: 2467–2474

Selected projects

  • Berlin Institute of Health – CRG2 ConDi (2014 – 2018)

  • European Commission Marie-Curie ITN (2011-2015)

  • European Commission FP7-IP CardioGeNet (2009-2013)

  • European Commission FP6-IP HeartRepair (2006-2010)

  • DAAD Sandwich PhD scholar – host (2008-2010) und (2011-2014)

  • Studienstitfung des Deutschen Volkes PhD scholar – host (2006 – 2009) and (2010 – 2012)

  • DFG Research grant RI2061/4-1

  • BMBF BioProfile grant 0313349 (2005 – 2007)

  • BMBF BioProfile grant 0313040B (2003 – 2006)

Membership in scientific bodies/juries

  • German Society of Cardiology, Member (since 2010)

  • Germany Society of Human Genetics, Member (since 2003)

  • European Society of Human Genetics, member (since 2003), elected Board Member (2005-2010)

  • European Society of Cardiology, Fellow (since 2010)

  • Working Group Development, Anatomy and Pathology of the European Society of Cardiology, elected Board Member (since 2012) and treasure (since 2015)

Media coverage

  • siehe:

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • married to Dr Andreas Rickert

  • two children


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