Short CV/Education and training

  • 1991 – 1996
    Studies of Chemistry, University of Dortmund, Germany. Diploma thesis entitled "Structural analysis of the protonation of and metal coordination to nucleobases: Analogies and differences" in Bioinorganic Chemistry under the supervision of Prof. Dr. B. Lippert, Department of Chemistry, University of Dortmund, Germany

  • 1996 – 2000
    Graduate research fellow with Prof. Dr. B. Lippert, Department of Chemistry, University of Dortmund, Germany. Ph.D. thesis "Structural investigation of metal ion coordination to model nucleobases"

  • 2000 – 2003
    Postdoctoral research fellow with Prof. Dr. C. Kisker, Center for Structural Biology, SUNY Stony Brook, NY, USA

  • 2003 – 2008
    Oberassistentin in the group of Prof. Dr. H. G. H. Berke, Institute of Inorganic Chemistry, University of Zürich

  • 2008 – 2014
    SNSF Professorship of the Swiss National Science Foundation, Institute of Inorganic Chemistry, University of Zürich

Selected publications

  • T. Huber, E. Freisinger, "Sulfide ions as modulators of metal-thiolate cluster size in a plant metallothionein", Dalton Trans. 2013, 42, 8878-8889 (doi: 10.1039/C3DT32438A).

  • J. Loebus, E. A. Peroza, N. Blüthgen, T. Fox, W. Meyer-Klaucke, O. Zerbe*, E. Freisinger, "Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1: the second part of the puzzle", J. Biol. Inorg. Chem. 2011, 16, 683-694 (doi: 10.1007/s00775-011-0770-2).

  • E. A. Peroza, R. Schmucki, P. Güntert, E. Freisinger, O. Zerbe, "The gE-domain of wheat Ec-1 metallothionein: A metal-binding domain with a distinctive structure", J. Mol. Biol. 2009, 387, 207-218 (doi: 10.1016/j.jmb.2009.01.035).

  • E. Freisinger, Review Article and Journal Cover, "Plant MTs – long neglected members of the metallothionein superfamily", Dalton Trans. 2008, 6663-6675 (doi: 10.1039/b809789e). Article also featured in: Chemical Biology 2009, 4, B4.

  • E. Freisinger, R. K. O. Sigel, "From nucleotides to ribozymes – A comparison of their metal ions binding properties", Coord. Chem. Rev. 2007, 251, 1834-1851 (doi: 10.1016/j.ccr.2007.03.008).

  • E. A. Peroza, E. Freisinger, "Metal ion binding properties of Triticum aestivum Ec-1 metallothionein: Evidence supporting two separate metal-thiolate clusters", J. Biol. Inorg. Chem. 2007, 12, 377-391 (doi: 10.1007/s00775-006-0195-5).

  • E. Freisinger, A. P. Grollman, H. Miller, C. Kisker, "Lesion (in)tolerance reveals insights into DNA replication fidelity", EMBO J. 2004, 23, 1494-1505 (doi: 10.1038/sj.emboj.7600158).

Complete list of publications

Selected projects

  • 1) Plant metallothioneins

  • 2) Site-specific modification of nucleic acids

Membership in scientific bodies/juries

University of Zurich:

  • Head of Working Group 2 (Emerging nucleic acid targets (beyond the double helix)) of the COST Action CM1105 (Functional metal complexes that bind to biomolecules), since 2012 (until 2016)

  • Advisory board member for the Peer Mentoring Program NCCR Structural, Biology Female Scientists in Structural Biology, since 2009

  • Head of the curriculum committee of the Department of Chemistry, since 2009

  • Representative of the associated members in the steering committee of the PD association, 2006 – 2010

  • Member of the steering committee of the Graduate School Chemical and Molecular Sciences Zurich (CMSZH), since 2006

  • Member of the Studienkommission of the Faculty, since 2006

  • Member of the committee for the Tag der offenen Türe, MNF-Tag, Student-Visiting day of the Department of Chemistry, since 2004

  • Study advisor of the Institute of Inorganic Chemistry, since 2004

Member of the Following Chemical Societies:

  • Chemical Society Zurich (CGZ), since 2008

  • Society of Biological Inorganic Chemistry (SBIC), since 2003

  • Swiss Chemical Society (SCG), since 2005

  • Swiss Society for Crystallography (SSCr), since 2004


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