Short CV/Education and training

  • 1986 – 1992
    Degree in Medicine and MD, University of Pavia, Italy

  • 1992 – 1993
    Clinical trainee in Haematology, University of Pavia, Italy

  • 1993 – 1994
    Clinical Scientist, University of Mnachester

  • 1994 – 1998
    PhD in Gene Therapy of Hematopoietic stem cells, University of Manchester

  • 1998 – 2001
    Research Associate, Imperial College London

  • 2001 – 2005
    Senior Scientist and Hin Lecturer in Stem Cell Biology, University of Manchester

  • 2005 – 2009
    Lecturer in Bone Biology, UoS

  • 2010 – 2012
    Senior Lecturer in Bone Biology, UoS

  • 2013
    Reader In Stem Cells and Skeletal Ageing, UoS

  • Since 2013
    Prof. In Musculoskeletal Ageing, University of Sheffield (UoS)

Selected publications

  • ST Mohanty, CJ Cairney, AD Chantry, S Madan, J Fernandes, SJ Howe, HD Moore, MJ Thompson, B Chen, A Thrasher, WN Keith, I Bellantuono A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion and engraftment to bone marrow in NOD/SCID mice, Stem Cells 30(6):1134-43, 2012

  • A Gambardella, C.K. Nagaraju, P.J. O?Shea, S.T. Mohanty, L. Kottam, J. Pilling M. Sullivan, M. Djerbi , W. Koopmann, P.I.Croucher and I Bellantuono. Glycogen synthase kinase-3alpha/beta inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage JBMR 26(4):811-21, 2011

  • I Bellantuono*, Aldahmash A and Kassem M*: Aging of marrow stromal stem cells and their contribution to age related bone loss. BBA 1792(4):364-70

  • RF Wynn, CA Hart, LO?Neill, JE Wraith, LJ Fairbairn and I Bellantuono. A small proportion of Mesenchymal stem cells strongly express functionally active CXCR4 receptor capable of promoting migration to bone marrow, Blood 104: 2643-5, 2004

  • M A Baxter, R F Wynn, S N Jowitt, J E Wraith, L J Fairbairn, and I Bellantuono. Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion StemCells, 22, 675-682, 2004

  • I.Bellantuono, L.Gao, S. Parry, S. Marley, F.Dazzi, J.M. Goldman, and H.J. Stauss Two distinct HLA-A0201-presented epitopes of the Wilms Tumour Antigen 1 can function as targets for leukaemia-reactive CTL. Blood 100 3835-3837, 2002


Selected projects

  • Identification of drugs which delay stem cell ageing

  • Computational models of bone formation and resorption to predict changes in bone in preclinical studies

  • The role of the bone microenvironment in the development of Myelodysplastic Syndromes

  • Stem cells and cell senescence

Membership in scientific bodies/juries

  • Deputy Chair of the Bioscience Skills and Career Strategy panel, Biotechnology and Biological Sciences Research Councils (since 2013)

  • Member of the NC3R Aged Rodent Group (since 2013)

Media coverage

  • New scientist August 2012: http://www.newscientist.com/article/mg21528784.600-protecting-prion-protein-keeps-stem-cells-young.html#.VFoJwE1ybIU

Soft Skills/Other activities and achievements

Soft Skills

  • Trained mentor


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