Short CV/Education and training

  • 1976 – 1978
    Guy Newton Junior Research Fellow, Wolfson College, Oxford

  • 1978 – 1980
    Royal Society European Post-doctoral Fellow, Service de Biochimie, Centre d'Etudes, Nucleaires de Saclay, Gif-sur-Yvette, France

  • 1980 – 1982
    Cystic Fibrosis Research Fellow, Biochemistry Department, St Mary's Hospital Medical School, London

  • 1982 – 1984
    MRC Senior Research Fellow, Biochemistry Department, St Mary's Hospital Medical School, London

  • 1984 – 1986
    MRC Senior Research Fellow, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford

  • 1986 – 1989
    MRC External Staff, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford

  • 1989 – 1992
    MRC External Staff, Molecular Genetics Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford; Fellow, Green College, Oxford; University Research Lecturer, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford

  • 1992 – 1994
    MRC Research Director, MRC Clinical Sciences Centre, Royal Post Graduate Medical School, Hammersmith Hospital, London; Professor Molecular Genetics, University of London

  • 1995
    MRC External Staff, Head of the Molecular Genetics Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford; Fellow, Green College, Oxford

  • 1995 – 1998
    Professor of Genetics, Genetics Unit, Department of Biochemistry, University of Oxford; Associate Director for the Department of Biochemistry, University of Oxford, Fellow Keble College, Oxford

  • Since 1998
    Fellow, Hertford College, Oxford

  • Since 1998
    Dr Lee's Professor of Anatomy, University of Oxford

  • 1998 – 2005
    Dr Lee's Professor of Anatomy, Head of Department, Department of Human Anatomy and Genetics, University of Oxford

  • Since 1999
    Director (honorary), MRC Functional Genomics Unit

  • 2005 – 2008
    Associate Head, Department of Physiology, Anatomy and Genetics, University of Oxford

  • 2008 – 2011
    Head of Department, Department of Physiology, Anatomy and Genetics

  • Since 2011
    Associate Head (Development, Impact and Equality), Medical Sciences Division

Selected publications

  • Jeans AF, Oliver PL, Johnson R, Capogna M, Vikman J, Molnár Z, Babbs A, Partridge CJ, Salehi SA, Bengtsson M, Eliasson L, Rorsman P, Davies KE (2007) A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating and ataxia in the blind-drunk mouse, Proc Nat.Acad. Sci 104: 2431-2436.

  • Becker EB, Oliver PL, Glitsch MD, Banks GT Achilli F, Hardy A, Nolan PM, Fisher EM, Davies KE (2009) A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. Proceedings of the National Academy of Sciences, USA 106: 6706-6711.

  • Goyenvalle A, Babbs A, van Ommen G-J, Garcia L, Davies KE (2009) Enhanced exon-skipping induced by U7snRNA carrying a splicing silencer sequence: promising tool for DMD therapy. Molecular Therapy 17: 1234-1240.

  • Oliver PL, Davies KE (2009) Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk. Human Molecular Genetics 18: 4576-4589.

  • Tinsley JM, Fairclough RJ, Storer R, Wilkes FJ, Potter AC, Squire SE, Powell DS, Cozzoli A, Capogrosso RF, Lambert A, Wilson FX, Wren SP, de Luca A, Davies KE (2011) Daily treatment with SMT C1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse. PLoS One 6: e19189.

  • Oliver PL, Finelli MJ, Edwards B, Bitoun E, Butts DL, Becker EBE, Cheeseman MT, Davies B, Davies KE (2011) Oxr1 is essential for protection against oxidative stress-induced neurodegeneration. PLoS Genetics Sep:7(10):e1002338.

  • Oliver PL, Sobczyk MV, Maywood ES, Edwards B, Lee S, Livieratos A, Oster H, Butler R, Godinho SIH, Wulff K, Peirson SN, Fisher SP, Chesham JE, Smith JW, Hastings MH, Davies KE, Foster RG (2012) Disrupted circadian rhythms in a mouse model of schizophrenia. Current Biology 22: 1-6.

  • Goyenvalle A, Davies KE (2012) Engineering multiple U7snRNA constructs to induce single and multiexon-skipping for Duchenne muscular dystrophy. Molecular Therapy. doi: 10.1038/mt.2012.26.

  • Goyenvalle A, Babbs A, Wright J, Wilkins V, Powell P, Garcia L, Davies KE (2012) Rescue of severely affected Dystrophin/Utrophin deficient mice through scAAV-U7snRNA mediated exon skipping. Human Molecular Genetics 21: 2559-2571.

  • Gehrig SM, van der Poel C, Sayer TA, Schertzer JD, Henstridge DC, Church JE, Lamon S, Russell AP, Davies KE, Febbraio MA, Lynch GS (2012) HSP72 preserves muscle function and slows progression of severe muscular dystrophy. Nature 484: 394-398.


Membership in scientific bodies/juries

Current Membership of Committees/Boards (selection):

  • Deputy Chairman, Wellcome Trust, 2013 – 2017

  • Scientific Advisory Board, Roslin Institute, Edinburgh, since 2013

  • Governor, The Lister Institute of Preventive Medicine, since 2012

  • Board of Directors, The American Society of Human Genetics, USA, 2011 – 2013

  • Scientific Advisory Board, Prosensa, since 2009

Current Membership of Committee/Boards for the University of Oxford (selection):

  • Member of Council, since 2012

  • REF 2014 Central Committee

  • Research Committee, 2012 – 2014

  • MSD Member of the Electoral Board, Rhodes Professorship of Clinical Pharmacology and Experimental Therapeutics

  • Personnel Committee

Current Membership of Editorial Boards (selection):

  • Executive Editor, Human Molecular Genetics (Founding Editor), since 1992

  • Editor, Journal of Gene Medicine (Founding Editor), since 1998

  • Section Editor F1000, since 2004

  • Consulting Editor, The Journal of Physiology, since 2011

Membership of Societies:

  • Founding Member of the Academy of Medical Sciences

  • European Molecular Biology Organisation (EMBO) (by election)

  • Fellow, Royal College of Pathologists (by election)

  • Academia Europaea (by election)

  • Honorary Member, Royal College of Physicians (by election)

  • British Society of Human Genetics

  • Biochemical Society

  • Genetics Society

  • European Working Group on Human Gene Transfer and Therapy

  • American Society of Human Genetics

  • European Human Genetics Society

  • British Society for Developmental Biology

  • Physiological Society

  • British Association

  • Royal Institution

  • Society of Neuroscience, USA

Media coverage

Selection of recent interviews:

  • Interview/video for the Physiology Society "Genomics and Physiology" 21st March, 2013

  • Interview for Oxford Mail for Town and Gown Fun Run. 27th March 2013

  • Interview for Research Fortnight. 25th July 2013

  • Video for the Centenary Programme criterion 'To improve staff knowledge and understanding of both the aims and strategy of the MRC'. 29th July 2013

  • Interview to help with Eli's Fund – 23rd February 2012

Contact

You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here

Testimonials

  1. Read what our members say about AcademiaNet.

No more excuses!

  1. Please download the brochure "No more excuses" and read more about female experts in Europe, and about AcademiaNet.

Similar profiles

  1. PhD Mar Albà

    Biological and related sciences Evolution, genomics, bioinformatics

  2. Prof. Patrizia Agostinis

    Biological and related sciences , HealthCell Biology, Cellular signaling, Cancer biology, Cancer therapy

  3. Dr. Chantal Abergel

    Biological and related sciences , Physical sciencesEnvironmental virology, Molecular and structural biology, biochemistry

  4. Dr. Jessica Abbott

    Biological and related sciences Evolutionary biology, Evolutionary genetics

 

News

  1. Possible Cure for Genetic Disease

    Duchenne muscular dystrophy is a congenital disease causing muscle degeneration and eventual death in adolescence. Now an international research team developed an active substance to combat this disease and tested it successfully.