Short CV/Education and training

  • 1994
    BSc Biology (1st Class Honours), University of Nottingham, UK

  • 1998
    PhD in Immunology, Wellcome Trust Prize Studentship, University of Bath, UK

  • 1997 – 2000
    Postdoctoral Fellow, University of Birmingham (Prof. P. Lane)

  • 2000 – 2003
    Wellcome Trust International Prize Travelling Fellow. University of California San Francisco, USA (Prof. Abul Abbas)

  • 2004 – 2008
    MRC Career Development Fellow, Division of Immunity & Infection, University of Birmingham (Senior Lecturer)

  • 2009 – 2012
    MRC Senior Non Clinical Research Fellow, Division of Immunity & Infection, University of Birmingham (Reader)

  • 2013
    Professor of Immune Regulation, University College London

Selected publications

  • Kenefeck, R., Wang, C. J., Kapadi, T., Wardzinski, L., Attridge, K., Clough, L. E., Heuts, F., Kogimtzis, A., Patel, S., Rosenthal, M., Ono, M., Sansom, D. M., Narendran, P., and Walker, L. S. Follicular helper T cell signature in type 1 diabetes. Journal of Clinical Investigation (2015) 125, 292-303

  • Wang, C., Heuts, F., Ovcinnikovs, V., Wardzinski, L., Bowers, C., Schmidt, E. M., Kogimtzis, A., Kenefeck, R., Sansom, D. M., and Walker, L. S. CTLA-4 controls follicular helper T cell differentiation by regulating the strength of CD28 engagement. Proc Natl Acad Sci U S A (2015) 112(2):524-9

  • Schubert, D., Bode, C., Kenefeck, R., Hou, T., Wing, J., Kennedy A., Bulashevska, A. al, Sakaguchi, S., Walker, L. S*., Sansom, D. M.*, and Grimbacher, B*. Autosomal dominant immune dysregulation syndrome in humans with CTLA-4 mutations. *Shared Senior Authorship. Nature Medicine (2014) 20:1410-1416

  • Attridge, K., Wang, C. J., Wardzinski, L., Kenefeck, R., Chamberlain, J. L., Manzotti, C., Kopf, M., and Walker, L. S. IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. Blood (2012) 119, 4656-4664

  • Qureshi, O. S., Zheng, Y., Nakamura, K., Attridge, K., Manzotti, C., Schmidt, E. M., Baker, J., Jeffery, L. E., Kaur, S., Briggs, Z., Hou, T. Z., Futter, C. E., Anderson, G., Walker, L. S., and Sansom, D. M. Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science (2011) 332, 600-603

  • Lucy S.K. Walker, Anna Chodos, Mark Eggena, Hans Dooms and Abul K. Abbas. Antigen-specific proliferation of CD4+CD25+ regulatory T cells in vivo. Journal of Experimental Medicine. (2003) 198(2):249-258.

Complete list of publications

Membership in scientific bodies/juries

  • NC3Rs Grant Assessment Panel (2011-present)

  • MRC College of Reviewers for the Newton Fund

  • Chair, NC3Rs Strategic Panel (2015)

  • Diabetes UK Moffit Travelling Fellowship Interview Panel

  • JDRF Medical Scientific Review Community

  • Asthma UK Research Funding Committee (2009-2012)


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