Short CV/Education and training

Education / professional experience / academic appointments

  • 2002 – 2003
    Diploma work under the supervision of Prof. D. Neri (Swiss Federal Institute of technology Zurich (ETHZ), Zurich)

  • 2004
    Studies of Molecular Biology completed with Diploma Degree at the University of Zurich. Specialisations: Molecular Biology and Immunology/Biochemistry

  • 2004 – 2007
    PhD under the supervision of Prof. F. Sallusto and Prof. A. Lanzavecchia (Institute for Research in Biomedicine (IRB), Bellinzona)

  • 2007 – 2010
    Post-doctoral position in Prof. J. Tschopp's group (UNIL, Biochemistry Department)

  • 2010 – 2012
    Senior lecturer position in the group of Prof. J. Tschopp (UNIL, Biochemistry Department)

  • Since 2012
    Assistant Professor funded by the wiss National Science Foundation (SNSF) (University of Lausanne (UNIL), Biochemistry Department)

Selected publications

  • G. Guarda, C. Dostert, F. Staehli, K. Cabalzar, R. Castillo, A. Tardivel, P. Schneider and J. Tschopp. Activated T lymphocytes dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature, 2009 Jul 9; 460(7252):269-73

  • G. Guarda*, M. Zenger*, A. Yazdi, K. Schroder, I. Ferrero, P. Menu, A. Tardivel , C. Mattmann and J. Tschopp. Differential NLRP3 expression among hematopoietic cells. The Journal of Immunology, 2011 Feb 15;186:2529-2534

  • G. Guarda*, M. Braun*, F. Staehli, A. Tardivel, I. Förster, M. Farlik, T. Decker, R.A. Du Pasquier, P. Romero and J. Tschopp. Type I IFN inhibits IL-1 production and inflammasome activation. Immunity, 2011 Feb 25;34:213-223

  • F. Staehli, K. Ludigs, L.X. Heinz, I. Ferrero, M. Braun, K. Schroder, M. Rebsamen, A. Tardivel, C. Mattmann, H.R. MacDonald, P. Romero, G. Guarda*,° and J. Tschopp*. NLRC5-deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells. The Journal of Immunology, 2012 Apr 15;188: 3820-3828

    *Shared senior authorship; °Corresponding author

  • MC. Michallet, G. Rota and G. Guarda. Innate receptors for adaptive immunity. Current Opinion in Microbiology, 2013 Jun;16(3):296-302

  • K. Ludigs°, Q. Seguín-Estévez°, S. Lemeille°, I. Ferrero, G. Rota, S. Chelbi, C. Mattmann, H. R. MacDonald, W. Reith* and G. Guarda*. NLRC5 specifically transactivates MHC class I and related genes through a distinctive SXY module. Plos genetics, 2015 Mar, DOI:10.1371/journal.pgen.1005088 °These authors contributed equally to this work; *Shared senior authorship


Selected projects

  • European Research Council Starting Grant; project entitled: "NLRs AS TRANSCRIPTIONAL REGULATORS", 2013 – 2018

  • Swiss National Science Foundation Professorship; project entitled: "T CELL-INTRINSIC ROLE OF PATTERN RECOGNITION RECEPTORS", 2012 – 2016

Contact

You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here

Testimonials

  1. Read what our members say about AcademiaNet.

No more excuses!

  1. Please download the brochure "No more excuses" and read more about female experts in Europe, and about AcademiaNet.

Similar profiles

  1. Dr. Sonja-Verena Albers

    Biology, Molecular biology, molecular microbiology, biochemistry, membrane protein biochemistry

  2. Prof. Lital Alfonta

    Biology, Chemistry, Bioelectrochemistry, Synthetic Biology, Chemical Biology

  3. Dr. Irene Agyepong

    Human medicine, Humanmedizin, Public Health, Public Health, Public Health

  4. Prof. Dr. Heike Allgayer

    Biology, Human medicine