Short CV/Education and training

  • 1976
    Abitur (A-levels) at Lessing Gymnasium (grammar school), Frankfurt, Germany

  • 1976 – 1981
    Studied biology at the University of Konstanz, Germany

  • 1979
    Internship at the Max Planck Institute of Biochemistry in Martinsried, Germany

  • 1980
    Internship at the Max Planck Institute of Biophysics in Frankfurt

  • 1981
    Diplom degree in biology, University of Konstanz, Germany

  • 1982
    Language studies at École de langue et de civilisation françaises (ELCF) in Geneva, Switzerland

  • 1982 – 1986
    Research assistant (doctoral student) at the Institut de Biochimie Clinique, Faculty of Medicine, University of Geneva, Switzerland

  • 1986
    Doctor of Natural Science (Dr. rer. nat.) from the University of Geneva, Switzerland

  • 1986 – 1990
    Research associate at the Institut de Biochimie Clinique, Faculty of Medicine, University of Geneva, Switzerland

  • 1990 – 1993
    Research associate in the Department de Morphologie, Faculty of Medicine, University of Geneva, Switzerland

  • 1994 – 1997
    Research associate at the Physiological Institute, University of Freiburg, Germany; Habilitation (postdoctoral qualification) fellowship from the German Research Foundation (DFG)

  • 1996
    Habilitation in the field of physiology, University of Freiburg, Germany

  • 1997 – 2001
    Heisenberg Fellowship

  • 1997 – 2002
    Director of a working group at the Institute of Neurophysiology, University of Cologne, Germany

  • 1999
    venia legendi (authorisation to teach) in the field of physiology in the Faculty of Medicine at the University of Cologne

  • 2000
    Visiting professor at Baylor College of Medicine, Houston, TX, USA

  • 2002 – 2006
    Research associate at the Physiological Institute, University of Tübingen, Germany

  • 2003
    venia legendi (authorisation to teach) at the University of Tübingen, Germany

  • Since 2006
    Research associate in the Internal Medicine Section IV, University Hospital, Tübingen

  • 2006
    Professor by special appointment, University of Tübingen

Selected publications

  • Hennige, A.M. et al.: Overexpression of kinase negative protein kinase C in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. In: Diabetes 59(1), 2010. S. 119-127.

  • Ranta, F. et al.: Regulation of calcineurin activity in insulin secreting cells: Stimulation by Hsp90 during glucocorticoid-induced apoptosis. In: Cell. Signalling, 20(10), 2008. S. 1780-1786.

  • Ranta, F. et al.: Dexamethasone induces cell death in insulin secreting cells, an effect reversed by Exendin-4. In: Diabetes 55, 2006. S. 1380-1390.

  • Ullrich, S. et al.: SGK1 mediates glucocorticoid induced inhibition of insulin secretion. In: Diabetes 54(4), 2005. S. 1090-1099.

  • Peterhoff, M. et al.: Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice. In: Eur. J. Endocrinol. 149, 2003. S. 343-350.

  • Nakazaki, M. et al.: PKA-independent Potentiation of Insulin Secretion by cAMP is Impaired in SUR1 Null Islets. In: Diabetes 51, 2002. S. 3440-3449.

  • Abel, K.B. et al.: Not somatostatin-induced hyperpolarisation is accompanied by a sustained inhibition of insulin secretion in INS-1 cells. Activation of sulfonylurea K+ATP channels is not involved. In: Pflügers Arch. 432, 1996. S. 89-96.

  • Ullrich, S., Wollheim, C.B.: GTP-dependent inhibition of insulin secretion by epinephrine in permeabilized RINm5F cells. In: J. Biol. Chem. 263, 1988. S. 8615-8620.

  • Ullrich, S., Wollheim, C.B.: Expression of both alpha1- and alpha2-adrenoceptors in an insulin-secreting cell line. Parallel studies of cytosolic free Ca2+ and insulin release. In: Mol. Pharmacol. 28, 1985. S. 100-106.

  • Ullrich, S., Wollheim, C.B.: Islet cyclic AMP levels are not lowered during alpha2-adrenergic inhibition of insulin release. Studies with epinephrine and forskolin. In: J. Biol. Chem. 259, 1984. S. 4111-4115.


Selected projects

  • International Research Training Group GRK1302 (funded by the DFG): The PI3K signalling pathway in tumour growth and diabetes, 2010 - 2015

  • DFG-funded project from an individual proposal: Reduced insulin secretion in obesity-associated prediabetes: The role of serine-kinase-mediated inhibition of the IRS signalling pathway in ?-cells, 2010 - 2012

  • PhD colloquium at the Faculty of Medicine, University of Tübingen: Regulation of proliferative signalling pathways in insulin-secreting cells, 2010

Membership in scientific bodies/juries

Memberships:

  • American Diabetes Association (ADA)

  • European Association of the Study of Diabetes (EASD)

  • German Physiological Society (DPG)

  • German Society for Cell Biology (DGZ)

  • German Diabetes Society (DDG)

Referee activities:

  • Pflügers Archiv: European Journal of Physiology

  • Hormone and Metabolic Research

  • Life Sciences

  • Diabetes

  • Molecular Pharmacology

  • American Journal of Physiology

  • European Journal of Pharmacology

  • PLoS ONE

  • Pancreas

  • Cellular Physiology and Biochemistry

  • Diabetologia

  • Metabolism

Additional qualifications

  • Project director and biological safety officer

Teaching:

  • Plenary lecture: Physiology for Physicians, winter semester 1997/98 - summer semester 2006

  • Lectures in physiology for pharmacists (winter semester 1995/96 – summer semester 1997)

  • Physiology seminars, since 1994

  • Supervision of Diplom and PhD students, internships for medical and dentistry students, since 1990


Soft Skills/Other activities and achievements

Additional interests

  • Various cultural, cultural history and social interests


Soft Skills


Other activities and achievements/family

  • Two children


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