Short CV/Education and training

  • 1987 – 1990
    Registrar in Radiotherapy and Clinical Oncology – The Royal Marsden NHS Trust, London & Surrey

  • 1990 – 1994
    Clinical Research Fellow in Cancer Genetics and Honorary Senior Registrar in Clinical Oncology, The Institute of Cancer Research and Royal Marsden NHS Trust, London & Surrey

  • 1994
    Visiting Assistant Professor in Genetic Epidemiology & Fellow in Oncology, University of Utah, Salt Lake City, USA

  • 1994
    Honorary Consultant in Cancer Genetics & Oncology, St George’s Hospital, London

  • 1994 – 2010
    Team Leader in Translational Cancer Genetics, Institute of Cancer Research

  • 1994
    Honorary Consultant, Cancer Genetics & Clinical Oncology, Royal Marsden NHS, Foundation Trust

  • 2004 – 2009
    Head of Clinical Cancer Genetics Unit, Royal Marsden NHS Foundation Trust

  • 2004 – 2010
    Reader in Clinical Cancer Genetics, University of London

  • 2010
    Professor of Oncogenetics & Team Leader, Oncogenetics, Institute of Cancer Research

Selected publications

  • Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet. 2011;43(8):785-91. PMID: 21743467

  • Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom gentotyping array. Nat Genet. 2013; 45(4):385-91. PMID: 23535732.

  • Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. Nat Genet. 2013.;45(6):686-689. PMID:23666240.

  • A meta-analysis of 87,040 inidividuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet. 2014;46(10):1103-9. PMID:25217961.

  • Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet. 2015;47(4):367-72. PMID:25730763.

  • The evolutionary history of lethal metastatic prostate cancer. Nature 2015;520(7547):353-7. PMID: 25830880.

  • Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat Genet. 2015; 47(7):736-45. PMID: 26005866.

  • The contribution of rare variation to prostate cancer heritability. Nat Genet. 2016;48(1):30-5. Epub 2015 Nov 16. PMID: 26569126.


Additional qualifications

  • FRCP, Professor of Oncogenetics, Recognised Teacher of University of London in Cancer Genetics & Clinical Oncology


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