Short CV/Education and training

  • 1979 – 1983
    Ph.D. Student, Polish Academy of Sciences, Institute of Biochemistry and Biophysics, Warsaw, Poland; Advisor: Dr. Witold Filipowicz

  • 1984 – 1986
    Postdoctoral Fellow, Center for Cancer Research, MIT, Cambridge, MA; Advisor: Dr. Phillip A. Sharp

  • 1987 – 1989
    Research Associate, Center for Cancer Research, MIT, Cambridge, MA; Advisor: Dr. Phillip A. Sharp

  • 1989 – 1994
    Assistant Professor and Head of Laboratory, The Rockefeller University, New York, NY

  • 1994 – 2000
    Associate Professor and Head of Laboratory, The Rockefeller University, New York, NY

  • Since 2000
    Professor and Head of Laboratory, The Rockefeller University, New York, NY

  • Since 2009
    Evelyn Gruss-Lipper Professor and Head of Laboratory, The Rockefeller University, New York, NY

Selected publications

  • Konarska, M.M., Filipowicz, W., Domdey, H. and Gross, H.J. Formation of a 2'-phosphomonoester, 3',5'-phosphodiester linkage by a novel RNA ligase in wheat germ. Nature (London) 293, 112-116 (1981).

  • Konarska, M.M., Padgett, R.A. and Sharp, P.A. Recognition of cap structure in splicing in vitro of mRNA precursors. Cell 38, 731-736 (1984).

  • Konarska, M.M., Grabowski, P.J., Padgett, R.A. and Sharp, P.A. Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors. Nature 313, 552-557 (1985).

  • Konarska, M.M., Padgett, R.A. and Sharp, P.A. Trans-splicing of mRNA precursors in vitro. Cell 42, 165-171 (1985).

  • Konarska, M.M. and Sharp, P.A. Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell 46, 845-855 (1986).

  • Query, C.C. and Konarska, M.M. Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants. Molecular Cell 14, 343-354 (2004).

  • Konarska MM, Vilardell J, Query CC. Repositioning of the reaction intermediate within the catalytic center of the spliceosome. Molecular Cell. 2006 Feb 17;21(4):543-53.

  • Liu, L., Query, C.C. and Konarska, M.M. Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing. Nature Struct. Mol. Biol. 2007 Jun;14(6):519-26. Epub 2007 May 7.

  • Smith, D.J., Query, C.C., and Konarska, M.M. trans-Splicing to Spliceosomal U2 snRNA Suggests Disruption of Branch Site-U2 Pairing during Pre-mRNA Splicing. Mol Cell 2007 Jun 22;26(6):883-90.

  • Smith, D.J., Konarska, M.M., and Query, C.C. Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeast. Mol Cell. 2009 May 15;34(3):333-43. PMID: 19450531


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