Short CV/Education and training

  • Since 2019
    apl. Professor in Physical Biology at the Heinrich Heine University, Düsseldorf, Germany

  • 2007
    Habilitation in Physical Biology from the Heinrich Heine University, Düsseldorf, Germany

  • Since 2002
    Independent Group Leader at the Institute of Biological Information Processing, Structural Biochemistry (IBI-7), Forschungszentrum Jülich GmbH, Germany

  • 1999 – 2002
    Associate Research Scientist at the Department of Biological Sciences, Columbia University in the city of New York, New York, USA (Mentor: Professor Liang Tong)

  • 1996 – 1999
    Postdoctoral scientist at the Biophysics Department, Max Planck Institute for Medical Research, Heidelberg, Germany (Mentor: Professor Dietmar Manstein)

  • 1997
    PhD in Chemistry from the Department of Chemistry, Indian Institute of Technology Delhi, Delhi, India (Mentor: Professor M. N. Gupta)

Selected publications

  • Arinkin V. et al. Structural determinants underlying the adduct lifetime in the LOV proteins of Pseudomonas putida. In: The FEBS Journal 288, 4955–4972 (2021).

  • Röllen K. et al. Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy. In: Journal of Molecular Biology 428, 3721 – 3736 (2016).

  • Granzin J. et al. Structural evidence for the role of polar core residue Arg175 in arrestin activation. In: Scientific Reports 5, 15808 (2015).

  • Endres, S. et al. Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae. In: BMC Microbiol. 15, 30 (2015).

  • Circolone, F. et al. Structural Basis for the Slow Dark Recovery of a Full-Length LOV Protein from Pseudomonas putida. In: Journal of Molecular Biology 417, 362-374 (2012).

  • Granzin, J. et al. Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin. In: Journal of Molecular Biology 416, 611-618 (2012).

  • Batra, R. et al. Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease. In: Nature Structural Biology 8, 810-817 (2001).

  • Gupta et al. Polarity index: The guiding solvent parameter for enzyme stability in aqueous-organic cosolvent mixtures. In: Biotechnology Progress 13, 284-288 (1997).



Complete list of publications

Selected projects

  • Visual signal transduction pathway

  • Blue-light photoreceptors

  • Natively unfolded proteins

  • Novel enzymes

  • Protein-ligand interactions

  • Protein aggregation

Membership in scientific bodies/juries

  • Member, Helmholtz Management Academy, since 2009

Additional qualifications

  • Helmholtz Management Academy, Certified Manager: Training through Malik Management Zentrum St. Gallen, 2009 – 2011


Soft Skills/Other activities and achievements

Other activities and achievements/family

  • Family, 2 Children (born in 2002, 2005)


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