Dr. Irene Agyepong
Health, Public Health
Biological and related sciences, Health
Neuro-endocrine-immunology, Experimental rheumatology
Role of neuronal-like mechanisms used by non-neuronal cells to modulate inflammation, Dopaminergic pathways in rheumatic diseases, Stress-related effects on immune response, Neurotransmitter-immune cells interaction during aging, Sex-specific differences in the neurotransmitter-immune cells interaction
Travel bursary of the EULAR committee, 2016
Start-up price of the DGRh, 2015
English, German, Italian
Peifer, C.; Hagemann, V.; Claus, M.; Larra, M. F.; Broede, P.; Watzl, C.; Wascher, E.; Capellino, S.: Low self-reported stress despite immune-physiological changes in paramedics during rescue operations
EXCLI J. 20: 792-811 (2021)
van Nie, L.; Salinas-Tejedor, L.; Dychus, N.; Fasbender, Frank; Hülser, M.-L.; Cutolo, M.; Rehart, S.; Capellino, S.: Dopamine induces in vitro migration of synovial fibroblast from patients with rheumatoid arthritis
Sci. Rep. 10: 11928 (13 pp) (2020)
Capellino, S.; Claus, M.; Watzl, C.: Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine
Cell. Mol. Immunol. 17: 705-711 (2020)
Novaira HJ, Graceli JB, Capellino S, Schoeffield A, Hoffman GE, Wolfe A, Wondisford F, Radovick S. Development and characterization of novel rat anti-mERβ sera. Endocrinology. 2016;157(7):2844-52.
Capellino S, Cosentino M, Luini A, Bombelli R, Lowin T, Cutolo M, Marino F, Straub RH. Increased expression of dopamine receptors in synovial fibroblasts of rheumatoid arthritis patients – inhibitory effects of dopamine on IL-8 and IL-6. Arthritis Rheumatol. 2014;66(10):2685-93
Jenei-Lanzl Z, Capellino S, Kees F, Fleck M, Lowin T, Straub RH. Anti-inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis. Ann Rheum Dis. 2015;74(2):444-51
Capellino S, Gelder M, Weber K, Härle P, Straub RH. First appearance and location of catecholaminergic cells during experimental arthritis, and elimination by chemical sympathectomy. Arthritis Rheum 2012 ;64(4):1110
Capellino S, Cosentino M, Wolff C, Schmidt M, Grifka J, Straub RH. Catecholamine-producing cells in the synovial tissue during arthritis: modulation of sympathetic neurotransmitters as new therapeutic target. Ann Rheum Dis. 2010;69(10):1853-60.
Capellino S, Montagna P, Villaggio B, Soldano S, Straub RH, Cutolo M. Hydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia. Clin Exp Rheumatol. 2008;26(5):903-9
Straub RH, Grum F, Strauch U, Capellino S, Bataille F, Bleich A, Falk W, Schölmerich J, Obermeier F. Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation. Gut. 2008;57(7):911-21.
MARIE CURIE individual Fellowship (EU Horizon2020), Title: DeBoRA (Dopamine and bone metabolism in rheumatoid arthritis)
Start-up price funded by the DGRh, Title: The dopamine pathway: a potential therapeutic target for local treatment of rheumatoid arthritis
DFG funded grant (CA933/1-1) within the research unit FOR696 (Molecular Analyses and Interactions at Articular Interfaces), Title: Rolle von Tyrosin-Hydroxylase (TH) – positiven Zellen im Rahmen des Entzündungsgeschehens bei Arthritis
Speaker of the GEBIN (German Endocrine Brain Immune Network)
Member of the DGRh (Deutsche Gesellschaft für Rheumatologie) and DHV (Deutscher Hochschulverband)
Member of the faculty council at the medical faculty of the University of Duisburg-Essen, Germany, since 2017
Mother of two children (7 and 10 years old).
You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here
Health, Public Health
Biological and related sciences, Environment, Plant Ecology, Conservation Biology, Landscape Genomics
Biological and related sciences, Microbial bioelectrochemistry, Microbial electrophysiology
Biological and related sciences, Health, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology