Prof. Dr. Amparo Acker-Palmer
Biological and related sciences, Health, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology
Biological and related sciences, Health
Neuroscience (Psychoneuroendocrinology; Women's mental health; Neuroimaging; Genetics)
The effects of endogenous and exogenous factors on mental health, particularly the influence of early life stress and drugs on adolescents as well as the impact of sex hormones on women's brain and behaviour.
Of clinical relevance: alcohol use disorder, peripartum depression and premenstrual dysphoric disorder.
Science for Life Laboratory and National Molecular Medicine Program fellowships, 2017
Marie Skłodowska-Curie fellowship, 2015
Best project proposal of young researcher award from the Swedish Society of Medicine, 2013
Travel award from the European College of Neuropsychopharmacology, 2012
Gu X, Dubol M, Stiernman L, Wikström J, Hahn A, Lanzenberger R, Epperson CN, Bixo M, Sundström-Poromaa I, Comasco E. White matter microstructure and volume correlates of premenstrual dysphoric disorder. J Psychiatry Neurosci. 2022 Feb 23;47(1):E67-E76. doi: 10.1503/jpn.210143. PMID: 35197364.
Comasco E, Kopp Kallner H, Bixo M, Hirschberg AL, Nyback S, de Grauw H, Epperson CN, Sundström-Poromaa I. Ulipristal Acetate for Treatment of Premenstrual Dysphoric Disorder: A Proof-of-Concept Randomized Controlled Trial. Am J Psychiatry. 2021 Mar 1;178(3):256-265. doi: 10.1176/appi.ajp.2020.20030286. Epub 2020 Dec 10. PMID: 33297719.
Vrettou M, Nilsson KW, Tuvblad C, Rehn M, Åslund C, Andershed AK, Wallén- Mackenzie Å, Andershed H, Hodgins S, Nylander I, Comasco E. VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths. Eur Child Adolesc Psychiatry. 2019 Oct;28(10):1329-1340. doi: 10.1007/s00787-019-01293-w. Epub 2019 Feb 25. PMID: 30805764; PMCID: PMC6785645.
Skalkidou A, Poromaa IS, Iliadis SI, Huizink AC, Hellgren C, Freyhult E, Comasco E. Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study. Psychoneuroendocrinology. 2019 May;103:296-305. doi: 10.1016/j.psyneuen.2019.02.002. Epub 2019 Feb 7. PMID: 30776573.
Nylander I, Todkar A, Granholm L, Vrettou M, Bendre M, Boon W, Andershed H, Tuvblad C, Nilsson KW, Comasco E. Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. Mol Neurobiol. 2017 Oct;54(8):6225-6234. doi: 10.1007/s12035-016-0157-z. Epub 2016 Oct 5. PMID: 27709495; PMCID: PMC5583263
Comasco E, Hellgren C, Olivier J, Skalkidou A, Sundström Poromaa I. Supraphysiological hormonal status, anxiety disorders, and COMT Val/Val genotype are associated with reduced sensorimotor gating in women. Psychoneuroendocrinology. 2015 Oct;60:217-23. doi: 10.1016/j.psyneuen.2015.06.019. Epub 2015 Jul 2. PMID: 26189199.
Comasco E, Hahn A, Ganger S, Gingnell M, Bannbers E, Oreland L, Wikström J, Epperson CN, Lanzenberger R, Sundström-Poromaa I. Emotional fronto-cingulate cortex activation and brain derived neurotrophic factor polymorphism in premenstrual dysphoric disorder. Hum Brain Mapp. 2014 Sep;35(9):4450-8. doi: 10.1002/hbm.22486. Epub 2014 Feb 25. PMID: 24615932; PMCID: PMC4107029.
Brain Sex Hormones (BSH)
Emotions and Serotonin in relation to Premenstrual Dysphoric Disorder (EmSeP)
Reviewer panel member for the Swedish Research Council, since 2022
Editorial Board member of ‘British Journal of Psychiatry’ (Cambridge), since 2021
Editorial Board member of ‘Biological Psychiatry: Global Open Science’ (Society of Biological Psychiatry), since 2021
Management board member of the Centre for Women’s Mental Health during the Reproductive Lifespan, WoMHeR, Uppsala University, since 2020
Associate Editor of ‘Substance Use and Misuse’ (Taylor & Francis), since 2017
Ad-hoc member of examining committee of doctoral students half-time report and defense thesis, since 2016
Reviewer panel member for the European Foundation for Alcohol Research (ERAB), 2014
Reviewer Editor of ‘Frontiers in Public Mental Health’ journal (Frontiers), since 2013
Board member of Svenska Föreningen för Alkohol- och Drogforskning (SAD), 2011 – 2016
"Study that explores promising new approach for treating premenstrual dysphoric disorder", article on everydayhealth.com, December 2022
"Promising treatment for premenstrual dysphoric disorder, PMDD", article on sciencedaily.com, December 2022
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Biological and related sciences, Health, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology
Health, Academic Medicine
Biological and related sciences, Evolution, genomics, bioinformatics
Biological and related sciences, Cell Biology, Molecular Biology, Biochemistry, Microscopy