Dr. Ana Cvejic

Research Experience

• Since 2015
  Faculty member, Stem Cell Institute, Cambridge, UK
  
  

• Since 2012
  Principal Investigator, Department of Haematology, School of Clinical Medicine, University of Cambridge
  
  

• 2008 – 2012
  Research Associate, Department of Haematology, School of Clinical Medicine, University of Cambridge
  
  

• 2004 – 2004
  Research Scientist, Department of Biochemistry, Faculty of Science, University of Oulu, Finland
  
  

• 2002 – 2004
  Research Assistant, Laboratory of Neurobiology, Institute for Biological Research “Sinisa Stankovic”, Belgrade, Serbia
  
  

Education

• 2002
  M.Sc. Molecular Biology and Physiology, Department of Molecular Biology and Physiology, Faculty of Biology, University of Belgrade
  
  

• 1. Chapman MS, Ranzoni AM, Myers B, Williams N, Coorens T, Mitchell E, Butler T, Dawson K, Hook Y, Moor L, Robinson P, Hook E, Campbell P*, Cvejic A* (2020). Lineage tracing of human embryonic and foetal blood development through somatic mutations, available on bioRxiv.

• 2. Ranzoni AM, Tangherloni A, Berest I, Riva SG, Myers B, Strzelecka P, Xu J., Panada E, Mohorianu I, Zaugg J, Cvejic A (2020). Integrative single-cell RNA-seq and ATAC-seq analysis of human foetal liver and bone marrow haematopoiesis. Cell Stem Cell, doi: 10.1016/j.stem.2020.11.015.

• 3. Canu G, Athanasiadis EI, Grandy RA, Garcia-Bernardo J, Strzelecka PM, Vallier L*, Ortmann D*, Cvejic A* (2020). Analysis of Endothelial-to-Haematopoietic Transition at the Single Cell Level identifies Cell Cycle Regulation as a Driver of Differentiation. Genome Biology, 21(1):157.

• 4. Bica I, Andrés-Terré H, Cvejic A*, Liò P* (2020). Unsupervised generative and graph representation learning for modelling cell differentiation. Scientific Reports, 10(1):9790

• 5. Hernández PP*, Strzelecka PM, Athanasiadis EI, Hall D, Robalo AF, Collins CM, Boudinot P, Levraud JP*, Cvejic A* (2018). Single-cell transcriptional analysis reveals ILC-like cells in zebrafish. Science Immunology, 3(29). pii: eaau5265.

• 6. Athanasiadis EI, Botthof JG, Andres H, Ferreira L, Lio P, Cvejic A (2017). Single-cell RNA-Sequencing uncovers transcriptional states and fate decisions in haematopoiesis. Nature Communications, 8(1):2045.

• 7. Botthof JG, Bielczyk-Maczyńska E, Ferreira L, Cvejic A (2017). Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish. PNAS, 114(22):E4452-E4461.

• 8. Carmona SJ, Teichmann SA*, Ferreira L, Macaulay IC, Stubbington MJT, Cvejic A*, Gfeller D* (2017). Single- cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types. Genome Research, 27(3):451-461

• 9. Dee CT, Nagaraju TR, Athanasiadis EI, Gray C, del Ama LF, Johnston SA, Secombes CJ*,♯, Cvejic A*,♯, and Hurlstone AFL*,♯ (2016). CD4-Transgenic Zebrafish Reveals Tissue Resident TH2- and Treg-like T cell Populations and Diverse Mononuclear Phagocytes. Journal of Immunology, 197(9):3520-30.

• 10. Macaulay IC, Svensson V, Labalette C, Ferreira L, Hamey F, Voet T, Teichmann S, Cvejic A (2016). Single cell RNA-sequencing reveals a continuous spectrum of differentiation in haematopoietic cells. Cell Reports, 14(4):966-7.

• 11. Bielczyk-Maczyńska E, Lam Hung L, Ferreira L, Fleischmann T, Weis F, Fernández-Pevida A, Harvey SA, Wali N, Warren AJ, Barroso I, Stemple DL, Cvejic A (2015). The ribosome biogenesis protein Nol9 is essential for definitive hematopoiesis and pancreas morphogenesis in zebrafish. PLOS Genetics, 11(12):e1005677.

• 12. Bielczyk-Maczyńska E, Serbanovic-Canic J, Ferreira L, Soranzo N, Stemple D, Ouwehand WH, Cvejic A (2014). A loss of function screen of identified genome-wide association study loci reveals new genes controlling haematopoiesis. PLOS Genetics, 10(7):e1004450.

• (♯corresponding author, *joint senior authors)

• ERC (European Research Council) Starting Grant, 2016 – 2021

• José Carreras Foundation – EHA Young Investigator Award, 2014 – 2017

• The Cancer Research UK Career Development Fellowship, 2012 – 2018

• Grant reviewer:

  Cancer Research UK, 2017; Biotechnology and Biological Sciences Research Council (BBSRC), 2016; Medical Research Council (MRC), project grant and QQ Reviewer, 2014, 2016, 2017(2x), 2019 (2x); Kay Kendall Leukaemia Fund (KKLF), 2013, 2014, 2017; Rosetrees Trust, 2018; Bloodwise, 2018; EMBO Long Term Fellowship 2018; Flanders Innovation and Entrepreneurship, Belgium 2018; Croatian Science Foundation, 2017; Austrian Science Fund (FWF), Austria, 2016, 2019, 2020; Icelandic Research Council, Iceland, 2016; Research Foundation Flanders (FWO), Belgium, 2015; Czech Science Foundation, Czech Republic, 2014, 2015; Swiss National Science Foundation, Switzerland, 2013, 2016.

• Journal reviewer:

  Nature, Cell, Science, Nature Methods, Nature Biotechnology, Nature Communications, Nature Cancer, PLoS Biology, Cell Reports, Blood, Nucleic Acids Research, Haematologica, Scientific Reports.

• Committee member:

  The Royal Society Research Grants B Panel (2021-2023); French Research Agency, ANR (Agence Nationale de la Recherche) 2020.

• I have been actively involved in “Women of Influence” initiative organised by Cancer Research UK (CRUK) (http://ow.ly/GdVNd). The initiative is committed to raise funding for young female scientists and to increase awareness of the scarcity of female scientists in the leading research positions. As a part of my commitment to promote gender equality in science I have given interviews for the Guardian, Daily Telegraph and Grazia.

• I also gave a talk and interview at the “The Sex in Science programme”, a joint initiative of the Wellcome Trust Sanger Institute and the EMBL-European Bioinformatics Institute (EBI) that aims to raise awareness about issues traditionally facing women in science. The footage can be found here: http://www.sanger.ac.uk/about/sex-science/distinguished-speakers.

• I have participated in public engagement activities funded and supported by the Stem Cell Institute, in collaboration with Cambridge Pint of Science, which aims to engage the public in understanding the latest in scientific research by delivering interesting and relevant talks and events in an accessible format. This included a podcast interview at which I explained in plain English work that is done in my group. I was also paired up with Cambridge-based painter Debbie Baxter to create a piece of art that represents my research interests, and offers a unique perspective on my work to a lay audience. The work was publicly displayed at the Michaelhouse Café’s exhibition space in Cambridge, where it was accessible to the general public.

• I have participated in London International Youth Science Forum (LIYSF). LIYSF is a prestigious programme which attracts some of the best young scientists from around the world (16 -21yrs), including a contingent from developing countries.

Other activities and achievements/family

• A daughter, born in 2009 and son born in 2012

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