Dr. Einat Segev

Current position

• Since 2017
  Senior Scientist (equivalent to Assistant Professor in the US), Department of Plant and Environmental Sciences, Weizmann Institute of Science, Israel
  
  

Professional preparation

• 2017
  Harvard Medical School, Boston, MA, Marine Microbiology, Postdoc
  
  

• 2017
  MIT, Cambridge, MA, Microbial Nitrogen Metabolism, Senior Postdoc
  
  

• 2012
  The Hebrew University of Jerusalem, Israel, Microbiology, Ph.D.
  
  

• 2007
  The Hebrew University of Jerusalem, Israel, Oceanography, M.Sc.
  
  

• 2005
  The Hebrew University of Jerusalem, Israel, Biology and Geology, B.Sc.
  
  

Summary of past and current work

• During my M.Sc. I examined the influence of seawater Mg/Ca ratio on the resulting ratio in mineralized shells of unicellular marine eukaryotes named foraminifera. My findings provided important insight regarding the biological influences on metal incorporation into shells of microorganisms (Segev and Erez, Geochem. Geophys. Geosys., 2003).

• In my Ph.D. I undertook a challenging project aimed to reveal cellular processes that occur in dormant bacterial spores. I developed novel methodologies for molecular characterization of spores as they are inaccessible to common research approaches. My research revealed novel RNA dynamics in spores and transformed common knowledge of spore biology (Segev, Smith and Ben-Yehuda, Cell, 2012; Segev et al., Jbact, 2013).

• During my Postdoctoral research I established a novel model system to co-cultivate micro-algae and bacteria. Through the unique combination of approaches from microbiology and Earth sciences, I characterized the chemical crosstalk and physiological processes that govern a dynamic interaction between the micro-alga E. huxleyi and the Roseobacter bacterium P. inhibens. I conducted field studies which successfully linked several of the laboratory-based observations to the environment. (Segev et al., eLIFE, 2016; Dashkova, Segev, et al., Algal Res, 2016; Segev et al., Jphycol 2016; Segev et al., PloS ONE, 2015).

• As a new principal investigator, I am establishing a lab that focuses on the study of microbial interactions in the marine environment. One of my post-docs and myself have already published a paper about microbial interactions that lead to multicellularity in phytoplankton (Abada and Segev, 2018, Front Mar Sci).

• Abada A. and Segev E., Multicellular Features of Phytoplankton, Front Mar Sci, 5:144, 2018.

• Segev E., Wyche P. T., Kim K., Petersen J., Ellebrandt C., Vlamakis H., Barteneva N., Paulson N. J., Chai L., Clardy J., Kolter R., Dynamic metabolic exchange governs a marine algal-bacterial interaction, eLIFE, doi: http://dx.doi.org/10.7554/eLife.17473, 2016.

• Dashkova V., Segev E., Malashenkov D., Kolter R., Vorobjev I., Barteneva S. N., Microalgal cytometric analysis in the presence of endogenous autofluorescent pigments, Algal Res, 19: 370-380, 2016.

• Segev E., Castañeda I.S., Sikes E.L., Vlamakis H., Kolter R., Bacterial influence on alkenones in live microalgae, J Phycol, 52(1):125-130, 2016.

• Sinai L., Rosenberg A., Smith Y., Segev E., Ben-Yehuda S., The molecular timeline of a reviving bacterial spore, Mol Cell 57(4):695-707, 2015.

• Segev E., Tellez A., Vlamakis H., Kolter R., Morphological heterogeneity and attachment of Phaeobacter inhibens, PloS ONE, 10 (11), e0141300, 2015.

• Segev E., Rosenberg A., Mamou G., Sinai L. and Ben-Yehuda S., Molecular kinetics of reviving bacterial spores, J Bacteriol.,195(9):1875-82, 2013.

• Segev E., Smith Y. and Ben-Yehuda S., RNA dynamics in aging bacterial spores, Cell, 148 (1-2):139-49, 2012.

• Segev E. and Erez J., Effect of Mg/Ca ratio in seawater on shell composition in shallow benthic foraminifera, Geochem. Geophy. Geosy., 7, doi:10.1029/2005GC000969, 2006.

Other activities and achievements/family

• Two amazing kids

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