Dr. Emily Flashman

• Emily Flashman studied Biochemistry with Pharmacology at the University of Southampton, followed by a D.Phil. in Biochemistry/Cardiovascular Medicine at the University of Oxford. After a few years as a postdoctoral researcher with Prof. Chris Schofield in the Department of Chemistry, she was awarded a Royal Society Dorothy Hodgkin Fellowship in 2010 and a L'Oreal For Women In Science Fellowship in 2011. During this period her work focussed on the molecular mechanisms of human oxygen-sensing enzymes. In 2015, Emily was awarded a BBSRC New Investigator grant to pursue the molecular characterisation of potential plant oxygen-sensing enzymes, and her research interests now focus on developing mechanisms of enhancing abiotic stress tolerance.

• White MD and Flashman E (2016). Catalytic strategies of the non-heme iron dependent oxygenases and their roles in plant biology. Curr Opin Chem Biol.31: 126-135.

• Tarhonskaya H, Hardy AP, Howe EA, Loik ND, Kramer HB, McCullagh JS, Schofield CJ, Flashman E (2015). Kinetic investigations of the role of factor inhibiting hypoxia-inducible factor (FIH) as an oxygen sensor. J Biol Chem. 290: 19726-19742.

• Hancock RL, Dunne K, Walport LJ, Flashman E, Kawamura A (2015). Epigenetic regulation by histone demethylases in hypoxia. Epigenomics. 7: 791-811.

• Tarhonskaya H, Chowdhury R, Leung IK, Loik ND, McCullagh JS, Claridge TD, Schofield CJ and Flashman E (2014). Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen. Biochem J. 463: 363-372.

• Sanchez-Fernandez EM, Tarhonskaya H, Al-Qahtani K, Hopkinson RJ, McCullagh JS, Schofield CJ, Flashman E (2013). Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase. Biochem J. 449: 491-496.

• Flashman E, Hoffart LM, Hamed RB, Bollinger Jr JM, Krebs C, Schofield CJ (2010). Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen. FEBS J. 277: 4089-4099

• Member of Editorial Board, Scientific Reports

• Member of Editorial Advisory Panel, Biochemical Journal

• Member of Royal Society International Exchanges Scheme Panel

• https://www.timeshighereducation.com/news/research/research-intelligence-breaking-through-the-glass-ceiling/417209.article

Other activities and achievements/family

• 2 young children keep me busy outside of work!

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