Short CV/Education and training


  • 1995
    B.Sc, Kyoto University, Japan (Anatomy and Cell Biology)

  • 1997
    M.Sc, Kyoto University, Japan (Biophysics)

  • 2000
    Ph.D, Kyoto University, Japan (Biophysics)

Posts held:

  • 1996 – 1997
    Teaching Assistant, Department of Science, Kyoto University, Japan

  • 1997 – 1998
    JSTC Research Assistant (Ph.D), Kyoto University

  • 1998 – 2000
    JSPS Research fellow (Ph.D), Department of Science, Kyoto University

  • 2000 – 2001
    JSTC Postdoctoral research fellow, Kyoto University

  • 2001 – 2002
    ICRF Postdoctoral research fellow, Imperial Cancer Research Fund, Clare Hall Laboratories

  • 2002 – 2005
    HFSP and CRUK Postdoctoral research fellow, Cancer Research UK, London Research Institute, Clare Hall Laboratories

  • 2005 – 2007
    JSPS and CRUK Postdoctoral research fellow, Cancer Research UK, London Research Institute, Clare Hall Laboratories

  • 2007 – 2009
    CRUK Senior Cancer Research Fellow, Group Leader, Weatherall Institute of Molecular Medicine, University of Oxford

  • 2009 – 2013
    CRUK Senior Cancer Research Fellow, Group Leader, Sir William Dunn School of Pathology, University of Oxford


  • 1995 – 1997
    Japan Scholarship Foundation, Postgraduate Scholarship

  • 1998 – 2000
    Japan Society for Promotion of Science (JSPS) Research Fellowship for Young Scientist

  • 2000 – 2001
    Japan Science and Technology Corporation (JSTC) Postdoctoral Fellowship

  • 2001 – 2002
    Imperial Cancer Research Fund (ICRF) long-term Postdoctoral Fellowship

  • 2002 – 2005
    Human Frontier Science Program (HFSP) long-term Postdoctoral Fellowship

  • 2005 – 2007
    Japan Society for Promotion of Science (JSPS) Postdoctoral Fellowship for Research Abroad

  • 2007 – 2013
    Cancer Research UK Career Development Award

  • Since 2013
    Wellcome Trust Senior Research Fellowship

Current position:

  • Wellcome Trust Non-Clinical Senior Research Fellow

  • University Research Lecturer (honorary)

  • Group Leader in the Sir William Dunn School of Pathology, University of Oxford

Selected publications

  • Yata, K., Bleuyard, J. Y., Nakato, R., Ralf, C., Katou, Y., Schwab, R. A., Niedzwiedz, W., Shirahige, K., Esashi F. (2014) BRCA2 coordinates the activities of cell-cycle kinases to promote genome stability. Cell Rep. 7, 1547-59

  • Yata, K, Lloyd, J., Maslen, S., Bleuyard, J.Y., Skehel, M., Smerdon, S. J., Esashi, F. (2012) Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair. Mol. Cell 45, 371-83

  • Bleuyard, J.Y., Buisson, R., Masson, J.Y., Esashi, F. (2012) ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair. EMBO Rep. 13, 135-41

  • Esashi, F., Galkin V.E., Yu X., Egelman, E. West S.C., (2007). Stabilisation of RAD51 nucleoprotein filament by the C-terminal region of BRCA2. Nature Struc Mol Biol. 14, 468-474

  • Esashi, F., Christ, N., Gannon, J., Liu, Y., Hunt, T., Jasin, M., West S.C. (2005). CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature (Article), 434, 598-604

Complete list of publications

Selected projects


  • University of Oxford, Medical Sciences Division, Group Leader "Genome stability control in proliferating human cells", since 2007

  • Cancer Research UK, London Research Institute, Postdoctoral research "The role of familial breast cancer gene BRCA2 in genome stability" (with Dr Stephen C. West), 2001 – 2007

  • Kyoto University, M.Sc., Ph.D. and Postdoctoral research "The role of fission yeast Cut5 and Crb2 in cell cycle checkpoint control" ( with Prof. Mitsuhiro Yanagida), 1995 – 2001

  • Kyoto University, Final-year research pleacement "Analysis of mammalian egg maturation" (with Dr Noboru Manabe and Prof. Hazime Miyamoto), 1994 – 1995

  • Kyoto University, Summer research placement "Identification of Suppressor of Hairless/RBP-Jk targets" (with Dr Masashi Kawaichi and Prof. Tasuku Honjo), 1992

Membership in scientific bodies/juries

  • The Scientific Reports Editorial Board member in the area of Molecular Biology


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