Short CV/Education and training

  • 1987 – 1991
    BSc (1st class Hons), Biochemistry, University of Aberdeen

  • 1992 – 1997
    DPhil, University of Oxford. Supervisor: Prof N J Proudfoot

  • 1997 – 2000
    Postdoctoral Fellow, UC Berkeley, Michael Levine lab

  • 2000 – 2001
    Lecturer, Centre for Developmental Genetics, University of Sheffield

  • 2002 – 2007
    Lister Institute Research Fellow and Lecturer, Faculty of Life Sciences, University of Manchester

  • 2007 – 2009
    Lecturer, Faculty of Life Sciences, University of Manchester

  • 2009
    Senior Lecturer, Faculty of Life Sciences, University of Manchester

Selected publications

  • Saunders, A., Core, L.J., Sutcliffe, C., Lis, J.T. and Ashe, H.L. (2013). Extensive Polymerase pausing during Drosophila axes patterning enables high-level and pliable transcription. Genes & Development 27, 1146-1158.

  • Saunders, A. and Ashe, H.L. (2013). Taking a pause to reflect on morphogenesis. Cell 153, .

  • Sawala, A., Sutcliffe, C. and Ashe, H.L. (2012). A multi-step molecular mechanism for BMP extracellular transport in the Drosophila embryo. PNAS 109, 11222-7.

  • Harris, R. E., Pargett, M., Sutcliffe, C., Umulis, D. and Ashe, H. L. (2011). Brat promotes stem cell differentiation via control of a bistable switch that restricts BMP signalling. Developmental Cell 20, 72.

  • Harris, R. E. and Ashe, H. L. (2011). Cease and desist: modulating short-range Dpp signalling in the stem- cell niche. EMBO Reports 12, 519.

  • Yarunin, A., Harris, R. E., Ashe, M. P. and Ashe, H. L. (2011). Patterning of the Drosophila oocyte by a sequential translation repression program involving the d4EHP and Belle translational repressors. RNA Biology, 8, 1.

  • Wang, X., Harris, R.E., Bayston, L.J.and Ashe, H.L. (2008). Type IV collagens regulate BMP signalling in Drosophila. Nature 454, 72.

  • Miles, W.O., Jaffray, E., Campbell, S.G., Takeda, S., Bayston, L.J., Basu, S.P., Li, M., Raftery, L.A., Ashe, M.P., Hay, R.T. and Ashe, H.L. (2008). Medea SUMOylation restricts the signalling range of the Dpp morphogen in the Drosophila embryo. Genes and Development 22, 2578.

Selected projects

  • Wellcome Trust Enhancement Award – BMP-integrin signaling synergy

  • Wellcome Trust Programme Grant – Dynamic regulation of the Dpp signalling-responsive transcriptional network in the Drosophila embryo

  • BBSRC Project Grant – Stem cell fate: exploiting the Drosophila germline to unravel the role of a conserved translation repression complex

Membership in scientific bodies/juries

  • Wellcome Trust Peer Review College member

  • BBSRC Pool of Experts member


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