Short CV/Education and training

  • 1991
    Diplom degree in Chemistry, Ruprecht Karls University, Heidelberg

  • 1994
    PhD in Chemistry, Ruprecht Karls University, Heidelberg and Max-Planck Institute fuer Medizimische Forschung, Heidelberg

  • 1995
    Postdoctoral Fellow at MPI für Molekulare Physiologie, Dortmund

  • 1996
    EMBO LT Fellowship at the MRC-National Institute for Medical Research (MRC-NIMR), London

  • 1996 – 1998
    Marie-Curie Fellowship at the MRC-NIMR, London

  • 1998 – 2000
    Postdoctoral Fellow at the MRC-NIMR, London

  • 2000 – 2006
    Programme Leader Track at the MRC-NIMR, London

  • 2006 – 2015
    Programme Leader at the the MRC-NIMR, London

  • Since 2015
    Group Leader at the Francis Crick Institute, London

Selected publications

  • B. Stieglitz, R. R. Rana, M. G. Koliopoulos, A. C. Morris-Davies, V. Schaeffer, E. Christodoulou, S. Howell, N. R. Brown, I. Dikic, K. Rittinger, Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature 503, 422-426 (2013)

  • B. Stieglitz, A. C. Morris-Davies, M. G. Koliopoulos, E. Christodoulou, K. Rittinger, LUBAC synthesizes linear ubiquitin chains via a thioester intermediate. EMBO Rep 13, 840-846 (2012)

  • B. Stieglitz, L. F. Haire, I. Dikic, K. Rittinger, Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold. J Biol Chem 287, 20823-20829 (2012)

  • F. Autore, B. Pagano, A. Fornili, K. Rittinger*, F. Fraternali*, In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation. Biophys J 99, 3716-3725 (2010)

  • F. J. Ivins, M. G. Montgomery, S. J. Smith, A. C. Morris-Davies, I. A. Taylor, K. Rittinger, NEMO oligomerization and its ubiquitin-binding properties. Biochem J 421, 243-251 (2009)

  • J. Rapley, V. L. Tybulewicz*, K. Rittinger*, Crucial structural role for the PH and C1 domains of the Vav1 exchange factor. EMBO Rep 9, 655-661 (2008)

  • D. Jozic, N. Cardenes, Y. L. Deribe, G. Moncalian, D. Hoeller, Y. Groemping, I. Dikic*, K. Rittinger*, J. Bravo*, Cbl promotes clustering of endocytic adaptor proteins. Nat Struct Mol Biol 12, 972-979 (2005)

  • Y. Groemping, K. Lapouge, S. J. Smerdon, K. Rittinger, Molecular basis of phosphorylation-induced activation of the NADPH oxidase. Cell 113, 343-355 (2003)

Complete list of publications


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