Mieszczanek J, de la Roche M & Bienz M (2008) A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription. Proc Natl Acad Sci USA 105, 19324-19329.
Metcalfe C, Mendoza-Topaz C, Mieszczanek J & Bienz M (2010) Stability elements in the LRP6 cytoplasmic tail confer efficient signaling upon DIX-dependent polymerisation. J Cell Sci 123, 1588-1599.
Metcalfe C, Ibrahim AEK, Graeb M, de la Roche M, Schwarz-Romond T, Fiedler M, Winton DJ, Corfield A & Bienz M (2010) Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. Cancer Res 70, 6629-6638.
Miller TCR, Rutherford TJ, Johnson CM, Fiedler M & Bienz M (2010) Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor. J Mol Biol 401, 969-984.
Fiedler M, Mendoza-Topaz C, Rutherford TJ, Mieszczanek J & Bienz M (2011) Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating beta-catenin. Proc Natl Acad Sci USA 108, 1937-1942.
Metcalfe C & Bienz M (2011) Inhibition of GSK3 by Wnt signaling – two contrasting models. J Cell Sci 124, 3537-3544.
Mendoza-Topaz C, Mieszczanek J & Bienz M (2011) The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin’s interaction with Dishevelled. Open Biol 1, 110013.
Licchesi JDF, Mieszczanek J, Mevissen TE, Rutherford TJ, Akutsu M, Virdee S, Oualid FE, Chin JW, Ovaa H, Bienz M & Komander D (2011) An Ankyrin-repeat ubiquitin-binding domain determines TRABID’s specificity for atypical ubiquitin chains. Nature Struct Mol Biol 19, 62-71.
de la Roche M, Rutherford TJ, Gupta D, Veprintsev DB, Saxty B, Freund SM & Bienz M (2012) An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nature Commun 3, 680.
Miller TCR, Mieszczanek J, Sánchez-Barrena MJ, Rutherford TJ, Fiedler M & Bienz M (2013) Evolutionary adaptation of the fly Pygo PHD finger towards recognizing histone H3 tail methylated at arginine 2. Structure 21, 2208-2220.
de la Roche M, Ibrahim AEK, Mieszczanek J & Bienz M (2014) LEF1 and B9L shield beta-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors. Cancer Res, in press.