Short CV/Education and training


  • 1996
    Master’s degree in chemistry, Ecole Nationale Supérieure de Chimie de Montpellier, France

  • 1996
    Master’s degree in biology, DEA Biologie-Santé, University of Montpellier II, France

  • 2000
    Ph.D. in molecular pharmacology (defended on 21/06/2000), University Paris XI, France

  • 2013
    Habilitation to supervise Ph.D. students (HDR), University of Lille, France


  • 1996 – 2000
    Ph.D. in molecular pharmacology (Supervisor: Jean-François Mouscadet), Institut Gustave Roussy, CNRS, Villejuif, France

  • 2001 – 2005
    Postdoctoral fellow, then Research Scientist (Supervisor: Stewart T. Cole), Inserm, Institut Pasteur, Paris, France

  • 2006 – 2011
    Group Leader, Biology of Intracellular Pathogens Group, Inserm Avenir Team, Institut Pasteur Korea, Seoul, South Korea

  • Since 2011
    Research Director at Inserm, Team Head, Chemical Genomics of the Intracellular Mycobacteria Group, University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 – UMR 8204 – CIIL – Center for Infection and Immunity of Lille (Director: Camille Locht)

Selected publications

  • Marion E, Mycobacterial Toxin Induces Analgesia in Buruli Ulcer by Targeting the Angiotensin Pathways. Cell 157(7):1565-76 (2014)

  • Pethe K, Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nature Medicine. 19(9):1157-60 (2013)

  • Brodin P, High content phenotypic cell-based visual screen identifies M. tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling. PloS Pathogens Sep 9;6(9). pii: e1001100 (2010)

  • Christophe T, High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors. PloS Pathogens Oct;5(10):e1000645 (2009)

  • A.S. Pym, Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nature Medecine 9: 533-539 *equal contribution (2003)


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